TAS2R38, taste 2 receptor member 38, 5726

N. diseases: 149; N. variants: 5
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10246939
rs10246939
Entrez Id: 5726;8972
Gene Symbol: TAS2R38;MGAM
TAS2R38;MGAM
CUI: C1154610
Disease:
sensory perception of bitter taste
0.700 GeneticVariation GWASDB GWAS of human bitter taste perception identifies new loci and reveals additional complexity of bitter taste genetics. 23966204 2014
dbSNP: rs10246939
rs10246939
Entrez Id: 5726;8972
Gene Symbol: TAS2R38;MGAM
TAS2R38;MGAM
CUI: C2350521
Disease:
Taste Perception (mental process)
0.700 GeneticVariation GWASDB Sensitivity of genome-wide-association signals to phenotyping strategy: the PROP-TAS2R38 taste association as a benchmark. 22132133 2011
dbSNP: rs1726866
rs1726866
Entrez Id: 5726;8972
Gene Symbol: TAS2R38;MGAM
TAS2R38;MGAM
CUI: C2350521
Disease:
Taste Perception (mental process)
0.700 GeneticVariation GWASDB Sensitivity of genome-wide-association signals to phenotyping strategy: the PROP-TAS2R38 taste association as a benchmark. 22132133 2011
dbSNP: rs713598
rs713598
Entrez Id: 5726;8972
Gene Symbol: TAS2R38;MGAM
TAS2R38;MGAM
CUI: C2350521
Disease:
Taste Perception (mental process)
0.700 GeneticVariation GWASDB Sensitivity of genome-wide-association signals to phenotyping strategy: the PROP-TAS2R38 taste association as a benchmark. 22132133 2011
dbSNP: rs10246939
rs10246939
Entrez Id: 5726;8972
Gene Symbol: TAS2R38;MGAM
TAS2R38;MGAM
CUI: C0028754
Disease:
Obesity
0.010 GeneticVariation BEFREE In conclusion, <i>TAS2R38</i> rs10246939 variation was associated with Koreans' dietary intake and increased their risk of obesity. 31438650 2019
dbSNP: rs713598
rs713598
Entrez Id: 5726;8972
Gene Symbol: TAS2R38;MGAM
TAS2R38;MGAM
CUI: C0858600
Disease:
Taste sweet
0.010 GeneticVariation BEFREE The rs1761667 single nucleotide polymorphism (SNP) in the <i>CD36</i> gene has been linked to fat taste sensitivity, the rs35874116 SNP in the <i>TAS1R2</i> gene has been related to sweet taste preference, and the rs713598 SNP in the <i>TAS2R38</i> gene has been associated with aversion to bitter, green leafy vegetables. 29385734 2018
dbSNP: rs713598
rs713598
Entrez Id: 5726;8972
Gene Symbol: TAS2R38;MGAM
TAS2R38;MGAM
CUI: C0333519
Disease:
Caries (morphologic abnormality)
0.010 GeneticVariation BEFREE It can be concluded that variation in CA6 (T55M), DEFB1 (G-20A), and TAS2R38 (A49P) may be associated with car</span>ies experience in Turkish adults with a high level of dental plaque, lactobacilli count, and age and when saliva buffer capacity is low. 26377569 2016
dbSNP: rs713598
rs713598
Entrez Id: 5726;8972
Gene Symbol: TAS2R38;MGAM
TAS2R38;MGAM
CUI: C0011334
Disease:
Dental caries
0.010 GeneticVariation BEFREE It can be concluded that variation in CA6 (T55M), DEFB1 (G-20A), and TAS2R38 (A49P) may be associated with car</span>ies experience in Turkish adults with a high level of dental plaque, lactobacilli count, and age and when saliva buffer capacity is low. 26377569 2016
dbSNP: rs10246939
rs10246939
Entrez Id: 5726;8972
Gene Symbol: TAS2R38;MGAM
TAS2R38;MGAM
CUI: C0010278
Disease:
Craniosynostosis
0.010 GeneticVariation BEFREE This study replicates previous work which showed that the coding SNP rs10246939 in the TAS2R38 gene is associated with CRS. 24415641 2014
dbSNP: rs10246939
rs10246939
Entrez Id: 5726;8972
Gene Symbol: TAS2R38;MGAM
TAS2R38;MGAM
CUI: C1302401
Disease:
Adenoma of large intestine
0.010 GeneticVariation BEFREE Using a case-control study of 914 colorectal adenoma cases/1188 controls, we explored associations among colorectal adenoma risk, dietary intake, and genetic variation in 3 bitter-taste receptor genes: TAS2R38 (rs713598, rs1726866, rs10246939), TAS2R16 (rs846672), and TAS2R50 (rs1376251). 24083639 2013
dbSNP: rs1726866
rs1726866
Entrez Id: 5726;8972
Gene Symbol: TAS2R38;MGAM
TAS2R38;MGAM
CUI: C1302401
Disease:
Adenoma of large intestine
0.010 GeneticVariation BEFREE Using a case-control study of 914 colorectal adenoma cases/1188 controls, we explored associations among colorectal adenoma risk, dietary intake, and genetic variation in 3 bitter-taste receptor genes: TAS2R38 (rs713598, rs1726866, rs10246939), TAS2R16 (rs846672), and TAS2R50 (rs1376251). 24083639 2013
dbSNP: rs713598
rs713598
Entrez Id: 5726;8972
Gene Symbol: TAS2R38;MGAM
TAS2R38;MGAM
CUI: C1302401
Disease:
Adenoma of large intestine
0.010 GeneticVariation BEFREE Using a case-control study of 914 colorectal adenoma cases/1188 controls, we explored associations among colorectal adenoma risk, dietary intake, and genetic variation in 3 bitter-taste receptor genes: TAS2R38 (rs713598, rs1726866, rs10246939), TAS2R16 (rs846672), and TAS2R50 (rs1376251). 24083639 2013
dbSNP: rs1201607264
rs1201607264
Entrez Id: 5726;8972
Gene Symbol: TAS2R38;MGAM
TAS2R38;MGAM
CUI: C2364111
Disease:
Ageusia
0.010 GeneticVariation BEFREE The following data were determined for all the volunteers: alimentary frequency by clinical dieticians; genotyping of the G145C polymorphism in the TAS2r38 gene; cognitive status; sensorial (visual and hearing) acuity and drugs related to ageusia or dysgeusia. 21763010 2012
dbSNP: rs713598
rs713598
Entrez Id: 5726;8972
Gene Symbol: TAS2R38;MGAM
TAS2R38;MGAM
CUI: C2364111
Disease:
Ageusia
0.010 GeneticVariation BEFREE The following data were determined for all the volunteers: alimentary frequency by clinical dieticians; genotyping of the G145C polymorphism in the TAS2r38 gene; cognitive status; sensorial (visual and hearing) acuity and drugs related to ageusia or dysgeusia. 21763010 2012
dbSNP: rs10246939
rs10246939
Entrez Id: 5726;8972
Gene Symbol: TAS2R38;MGAM
TAS2R38;MGAM
CUI: C0850572
Disease:
Adenomatous polyp of colon
0.010 GeneticVariation BEFREE This study examined bitter taste genetics and whether variation in the TAS2R38 gene at three polymorphic loci (A49P, V262A and I296V) could alter dietary and systemic folate levels and dietary vitamin C intake, and whether a nutrigenetic circuit existed that might link bitter taste, folate/antioxidant status and risk for a colonic adenomatous polyp. 21769326 2011
dbSNP: rs1726866
rs1726866
Entrez Id: 5726;8972
Gene Symbol: TAS2R38;MGAM
TAS2R38;MGAM
CUI: C0850572
Disease:
Adenomatous polyp of colon
0.010 GeneticVariation BEFREE This study examined bitter taste genetics and whether variation in the TAS2R38 gene at three polymorphic loci (A49P, V262A and I296V) could alter dietary and systemic folate levels and dietary vitamin C intake, and whether a nutrigenetic circuit existed that might link bitter taste, folate/antioxidant status and risk for a colonic adenomatous polyp. 21769326 2011
dbSNP: rs713598
rs713598
Entrez Id: 5726;8972
Gene Symbol: TAS2R38;MGAM
TAS2R38;MGAM
CUI: C0850572
Disease:
Adenomatous polyp of colon
0.010 GeneticVariation BEFREE This study examined bitter taste genetics and whether variation in the TAS2R38 gene at three polymorphic loci (A49P, V262A and I296V) could alter dietary and systemic folate levels and dietary vitamin C intake, and whether a nutrigenetic circuit existed that might link bitter taste, folate/antioxidant status and risk for a colonic adenomatous polyp. 21769326 2011
dbSNP: rs139085046
rs139085046
Entrez Id: 5726;8972
Gene Symbol: TAS2R38;MGAM
TAS2R38;MGAM
CUI: C0027651
Disease:
Neoplasms
0.010 GeneticVariation BEFREE All three follicular cell lines, however, and the original tumor tissue showed the same p53 mutation (R273H) in MOH analysis and TGGE. 7725741 1995