PTGS1, prostaglandin-endoperoxide synthase 1, 5742

N. diseases: 318; N. variants: 36
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10306141
rs10306141
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute
C 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs10306152
rs10306152
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute
C 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs10306156
rs10306156
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute
T 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs10306157
rs10306157
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute
G 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs10306166
rs10306166
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute
G 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs10306182
rs10306182
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute
T 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs10306183
rs10306183
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute
C 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs10306184
rs10306184
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute
T 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs10306194
rs10306194
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute
C 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs3842802
rs3842802
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute
G 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs3842803
rs3842803
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute
T 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs4240474
rs4240474
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute
A 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs4240474
rs4240474
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute
G 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs4273915
rs4273915
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute
C 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs4836886
rs4836886
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute
T 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs4836888
rs4836888
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute
G 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs9299280
rs9299280
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute
A 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs10306121
rs10306121
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1
CUI: C0428474
Disease:
Serum LDL cholesterol measurement
0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs10306121
rs10306121
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1
CUI: C0202117
Disease:
Low density lipoprotein cholesterol measurement
0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs10306137
rs10306137
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1
CUI: C0428474
Disease:
Serum LDL cholesterol measurement
0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs10306137
rs10306137
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1
CUI: C1445957
Disease:
Serum total cholesterol measurement
0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs10306137
rs10306137
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1
CUI: C0202117
Disease:
Low density lipoprotein cholesterol measurement
0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs3842787
rs3842787
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1
CUI: C0030920
Disease:
Peptic Ulcer
0.030 GeneticVariation BEFREE Individuals with two single nucleotide polymorphisms (SNPs) of cyclooxygenase-1 (COX-1), A-842G and C50T, exhibit increased sensitivity to aspirin and lower prostaglandin synthesis capacity but the polymorphism lacked statistical significance in relation to an association with bleeding peptic ulcer. 26369686 2015
dbSNP: rs3842787
rs3842787
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1
CUI: C0030920
Disease:
Peptic Ulcer
0.030 GeneticVariation BEFREE Two single nucleotide polymorphisms (SNP) of cyclooxygenase-1 (COX-1), A-842G and C50T, exhibited increased sensitivity to aspirin and had lower prostaglandin synthesis capacity, lacking statistical significance in the association with bleeding peptic ulcer. 20586862 2010
dbSNP: rs3842787
rs3842787
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1
CUI: C0030920
Disease:
Peptic Ulcer
0.030 GeneticVariation BEFREE The adjusted risk for peptic ulcer bleeding among individuals who were </span>heterozygote for the A-842G/C50T polymorphism was 0.75 (range, 0.19-3.01) compared with wild type. 17078001 2006