PHRF1, PHD and ring finger domains 1, 57661

N. diseases: 17; N. variants: 5
Disease: Systemic Scleroderma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4963128
rs4963128
Entrez Id: 57661
Gene Symbol: PHRF1
PHRF1
CUI: C0036421
Disease:
Systemic Scleroderma 		0.010 GeneticVariation BEFREE Four out of five analysed SNPs were significantly associated with the presence of anticentromere autoantibodies (ACA) in the patients with SSc in the combined analysis (rs1131665: p(FDR)=6.14 × 10(-4), OR=0.78; rs4963128: p(FDR)=6.14 × 10(-4), OR=0.79; rs702966: p(FDR)=3.83 × 10(-3), OR=0.82; and rs2246614: p(FDR)=3.83 × 10(-3), OR=0.83). 21926187 2012