ZSWIM6, zinc finger SWIM-type containing 6, 57688

N. diseases: 95; N. variants: 15
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs587777695
rs587777695
Entrez Id: 57688
Gene Symbol: ZSWIM6
ZSWIM6
CUI: C1863616
Disease:
ACROMELIC FRONTONASAL DYSOSTOSIS 		T 0.800 GeneticVariation CLINVAR Acromelic frontonasal dysostosis and ZSWIM6 mutation: phenotypic spectrum and mosaicism. 26706854 2016
dbSNP: rs587777695
rs587777695
Entrez Id: 57688
Gene Symbol: ZSWIM6
ZSWIM6
CUI: C1863616
Disease:
ACROMELIC FRONTONASAL DYSOSTOSIS 		T 0.800 GeneticVariation CLINVAR Exome sequencing identifies a recurrent de novo ZSWIM6 mutation associated with acromelic frontonasal dysostosis. 25105228 2014
dbSNP: rs587777695
rs587777695
Entrez Id: 57688
Gene Symbol: ZSWIM6
ZSWIM6
CUI: C1863616
Disease:
ACROMELIC FRONTONASAL DYSOSTOSIS 		T 0.800 CausalMutation CLINVAR Exome sequencing identifies a recurrent de novo ZSWIM6 mutation associated with acromelic frontonasal dysostosis. 25105228 2014
dbSNP: rs587777695
rs587777695
Entrez Id: 57688
Gene Symbol: ZSWIM6
ZSWIM6
CUI: C1863616
Disease:
ACROMELIC FRONTONASAL DYSOSTOSIS 		0.800 GeneticVariation UNIPROT Exome sequencing identifies a recurrent de novo ZSWIM6 mutation associated with acromelic frontonasal dysostosis. 25105228 2014
dbSNP: rs7709645
rs7709645
Entrez Id: 57688
Gene Symbol: ZSWIM6
ZSWIM6
CUI: C0036341
Disease:
Schizophrenia 		0.800 GeneticVariation GWASCAT Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder. 22688191 2012
dbSNP: rs7709645
rs7709645
Entrez Id: 57688
Gene Symbol: ZSWIM6
ZSWIM6
CUI: C0036341
Disease:
Schizophrenia 		0.800 GeneticVariation GWASDB Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder. 22688191 2012
dbSNP: rs10223052
rs10223052
Entrez Id: 57688
Gene Symbol: ZSWIM6
ZSWIM6
CUI: C0021704
Disease:
Intelligence 		A 0.700 GeneticVariation GWASCAT A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence. 29326435 2019
dbSNP: rs13179617
rs13179617
Entrez Id: 57688
Gene Symbol: ZSWIM6
ZSWIM6
CUI: C0021704
Disease:
Intelligence 		T 0.700 GeneticVariation GWASCAT A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence. 29326435 2019
dbSNP: rs6449533
rs6449533
Entrez Id: 57688
Gene Symbol: ZSWIM6
ZSWIM6
CUI: C1305855
Disease:
Body mass index 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs7714712
rs7714712
Entrez Id: 57688
Gene Symbol: ZSWIM6
ZSWIM6
CUI: C1305855
Disease:
Body mass index 		A 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722 2019
dbSNP: rs7719676
rs7719676
Entrez Id: 57688
Gene Symbol: ZSWIM6
ZSWIM6
CUI: C0036341
Disease:
Schizophrenia 		G 0.700 GeneticVariation GWASCAT Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect. 30285260 2019
dbSNP: rs4490539
rs4490539
Entrez Id: 57688
Gene Symbol: ZSWIM6
ZSWIM6
CUI: C0596887
Disease:
mathematical ability 		A 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs74320437
rs74320437
Entrez Id: 57688
Gene Symbol: ZSWIM6
ZSWIM6
CUI: C0596887
Disease:
mathematical ability 		C 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs74419120
rs74419120
Entrez Id: 57688
Gene Symbol: ZSWIM6
ZSWIM6
CUI: C0596887
Disease:
mathematical ability 		T 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs74419120
rs74419120
Entrez Id: 57688
Gene Symbol: ZSWIM6
ZSWIM6
CUI: C0596887
Disease:
mathematical ability 		C 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs78922867
rs78922867
Entrez Id: 57688
Gene Symbol: ZSWIM6
ZSWIM6
CUI: C0032181
Disease:
Platelet Count measurement 		0.700 GeneticVariation GWASCAT Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. 29403010 2018
dbSNP: rs1554041295
rs1554041295
Entrez Id: 57688
Gene Symbol: ZSWIM6
ZSWIM6
CUI: C0036857
Disease:
Severe intellectual disability 		T 0.700 CausalMutation CLINVAR A Recurrent De Novo Nonsense Variant in ZSWIM6 Results in Severe Intellectual Disability without Frontonasal or Limb Malformations. 29198722 2017
dbSNP: rs587777695
rs587777695
Entrez Id: 57688
Gene Symbol: ZSWIM6
ZSWIM6
CUI: C0026827
Disease:
Muscle hypotonia 		T 0.700 CausalMutation CLINVAR A Recurrent De Novo Nonsense Variant in ZSWIM6 Results in Severe Intellectual Disability without Frontonasal or Limb Malformations. 29198722 2017
dbSNP: rs587777695
rs587777695
Entrez Id: 57688
Gene Symbol: ZSWIM6
ZSWIM6
CUI: C0432072
Disease:
Dysmorphic features 		T 0.700 CausalMutation CLINVAR A Recurrent De Novo Nonsense Variant in ZSWIM6 Results in Severe Intellectual Disability without Frontonasal or Limb Malformations. 29198722 2017
dbSNP: rs587777695
rs587777695
Entrez Id: 57688
Gene Symbol: ZSWIM6
ZSWIM6
CUI: C0000772
Disease:
Multiple congenital anomalies 		T 0.700 CausalMutation CLINVAR A Recurrent De Novo Nonsense Variant in ZSWIM6 Results in Severe Intellectual Disability without Frontonasal or Limb Malformations. 29198722 2017
dbSNP: rs72761442
rs72761442
Entrez Id: 57688
Gene Symbol: ZSWIM6
ZSWIM6
CUI: C0036341
Disease:
Schizophrenia 		A 0.700 GeneticVariation GWASCAT Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia. 28540026 2017
dbSNP: rs72761442
rs72761442
Entrez Id: 57688
Gene Symbol: ZSWIM6
ZSWIM6
CUI: C0008074
Disease:
Child Development Disorders, Pervasive 		A 0.700 GeneticVariation GWASCAT Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia. 28540026 2017
dbSNP: rs7720894
rs7720894
Entrez Id: 57688
Gene Symbol: ZSWIM6
ZSWIM6
CUI: C1305855
Disease:
Body mass index 		C 0.700 GeneticVariation GWASCAT Genome-wide association study identifies 112 new loci for body mass index in the Japanese population. 28892062 2017
dbSNP: rs587777695
rs587777695
Entrez Id: 57688
Gene Symbol: ZSWIM6
ZSWIM6
CUI: C0432072
Disease:
Dysmorphic features 		T 0.700 CausalMutation CLINVAR Acromelic frontonasal dysostosis and ZSWIM6 mutation: phenotypic spectrum and mosaicism. 26706854 2016
dbSNP: rs587777695
rs587777695
Entrez Id: 57688
Gene Symbol: ZSWIM6
ZSWIM6
CUI: C0026827
Disease:
Muscle hypotonia 		T 0.700 CausalMutation CLINVAR Acromelic frontonasal dysostosis and ZSWIM6 mutation: phenotypic spectrum and mosaicism. 26706854 2016