|
rs4919510
|
SEMA4G;MRPL43;MIR608
|
Primary malignant neoplasm of lung
|
|
0.050 |
GeneticVariation |
BEFREE |
A total of 37 patients with non-small cell lung cancer (NSCLC) were selected to determine the expression levels of miR-608; 96 NSCLC patients and 136 cancer-free healthy controls were recruited to determine the incidence of miR-608 rs4919510 in lung cancer patients.
|
31552102 |
2019 |
|
rs4919510
|
SEMA4G;MRPL43;MIR608
|
Carcinoma of lung
|
|
0.050 |
GeneticVariation |
BEFREE |
A total of 37 patients with non-small cell lung cancer (NSCLC) were selected to determine the expression levels of miR-608; 96 NSCLC patients and 136 cancer-free healthy controls were recruited to determine the incidence of miR-608 rs4919510 in lung cancer patients.
|
31552102 |
2019 |
|
rs4919510
|
SEMA4G;MRPL43;MIR608
|
Malignant neoplasm of lung
|
|
0.050 |
GeneticVariation |
BEFREE |
A total of 37 patients with non-small cell lung cancer (NSCLC) were selected to determine the expression levels of miR-608; 96 NSCLC patients and 136 cancer-free healthy controls were recruited to determine the incidence of miR-608 rs4919510 in lung cancer patients.
|
31552102 |
2019 |
|
rs4919510
|
SEMA4G;MRPL43;MIR608
|
Breast Carcinoma
|
|
0.050 |
GeneticVariation |
BEFREE |
Thus, the present study explored the association between five common functional polymorphisms in miRNAs (i.e., miRNA-196a2C>T, rs11614913; miRNA-146aG>C, rs2910164; miRNA-423C>A, rs6505162; miRNA-608G>C, rs4919510; miRNA-27aC>T, rs895819) and the risk of BC.
|
29782194 |
2018 |
|
rs4919510
|
SEMA4G;MRPL43;MIR608
|
Colorectal Carcinoma
|
|
0.050 |
GeneticVariation |
BEFREE |
The meta-analysis suggested that the microRNA-608 rs4919510 polymorphism maybe associate with a significantly decreased risk for colorectal cancer.
|
29909406 |
2018 |
|
rs4919510
|
SEMA4G;MRPL43;MIR608
|
Malignant neoplasm of breast
|
|
0.050 |
GeneticVariation |
BEFREE |
Thus, the present study explored the association between five common functional polymorphisms in miRNAs (i.e., miRNA-196a2C>T, rs11614913; miRNA-146aG>C, rs2910164; miRNA-423C>A, rs6505162; miRNA-608G>C, rs4919510; miRNA-27aC>T, rs895819) and the risk of BC.
|
29782194 |
2018 |
|
rs4919510
|
SEMA4G;MRPL43;MIR608
|
Primary malignant neoplasm of lung
|
|
0.050 |
GeneticVariation |
BEFREE |
Moreover, the RegulomeDB database indicated that rs4919510 may affect the expression of two nearby genes ( SEMA4G and MRPL43), and the Cancer Genome Atlas database revealed that the expression level of SEMA4G was significantly lower in colorectal cancer and lung cancer tissues than that in adjacent non-tumour tissues, while the expression level of SEMA4G was significantly higher in gastric cancer tissues than that in adjacent non-tumour tissues.
|
28653886 |
2017 |
|
rs4919510
|
SEMA4G;MRPL43;MIR608
|
Breast Carcinoma
|
|
0.050 |
GeneticVariation |
BEFREE |
In the present meta-analysis, no relationships between miR-608 rs4919510 polymorphism (C>G) and the risk of breast cancer were found.
|
28829821 |
2017 |
|
rs4919510
|
SEMA4G;MRPL43;MIR608
|
Malignant neoplasm of lung
|
|
0.050 |
GeneticVariation |
BEFREE |
Moreover, the RegulomeDB database indicated that rs4919510 may affect the expression of two nearby genes ( SEMA4G and MRPL43), and the Cancer Genome Atlas database revealed that the expression level of SEMA4G was significantly lower in colorectal cancer and lung cancer tissues than that in adjacent non-tumour tissues, while the expression level of SEMA4G was significantly higher in gastric cancer tissues than that in adjacent non-tumour tissues.
|
28653886 |
2017 |
|
rs4919510
|
SEMA4G;MRPL43;MIR608
|
Carcinoma of lung
|
|
0.050 |
GeneticVariation |
BEFREE |
Moreover, the RegulomeDB database indicated that rs4919510 may affect the expression of two nearby genes ( SEMA4G and MRPL43), and the Cancer Genome Atlas database revealed that the expression level of SEMA4G was significantly lower in colorectal cancer and lung cancer tissues than that in adjacent non-tumour tissues, while the expression level of SEMA4G was significantly higher in gastric cancer tissues than that in adjacent non-tumour tissues.
|
28653886 |
2017 |
|
rs4919510
|
SEMA4G;MRPL43;MIR608
|
Colorectal Carcinoma
|
|
0.050 |
GeneticVariation |
BEFREE |
Moreover, the RegulomeDB database indicated that rs4919510 may affect the expression of two nearby genes ( SEMA4G and MRPL43), and the Cancer Genome Atlas database revealed that the expression level of SEMA4G was significantly lower in colorectal cancer and lung cancer tissues than that in adjacent non-tumour tissues, while the expression level of SEMA4G was significantly higher in gastric cancer tissues than that in adjacent non-tumour tissues.
|
28653886 |
2017 |
|
rs4919510
|
SEMA4G;MRPL43;MIR608
|
Malignant neoplasm of breast
|
|
0.050 |
GeneticVariation |
BEFREE |
In the present meta-analysis, no relationships between miR-608 rs4919510 polymorphism (C>G) and the risk of breast cancer were found.
|
28829821 |
2017 |
|
rs4919510
|
SEMA4G;MRPL43;MIR608
|
Malignant neoplasm of lung
|
|
0.050 |
GeneticVariation |
BEFREE |
However, miR-196a2 rs11614913, miR-30c-1 rs928508, miR-608 rs4919510 and miR-27a rs895819 polymorphisms were not significantly associated with lung cancer risks in any models.
|
26973201 |
2016 |
|
rs4919510
|
SEMA4G;MRPL43;MIR608
|
Colorectal Carcinoma
|
|
0.050 |
GeneticVariation |
BEFREE |
Conflicting results are available on the association between rs4919510, a SNP in mature miR-608 and clinical outcome in CRC.
|
27381831 |
2016 |
|
rs4919510
|
SEMA4G;MRPL43;MIR608
|
Breast Carcinoma
|
|
0.050 |
GeneticVariation |
BEFREE |
In contrast, the miR-499 (rs3746444) AG/GG genotypes were associated with an increased risk of BC (OR = 1.45, 95% CI = 1.10-1.91), and miR-608 (rs4919510) was not significantly associated with BC risk.
|
26886638 |
2016 |
|
rs4919510
|
SEMA4G;MRPL43;MIR608
|
Primary malignant neoplasm of lung
|
|
0.050 |
GeneticVariation |
BEFREE |
However, miR-196a2 rs11614913, miR-30c-1 rs928508, miR-608 rs4919510 and miR-27a rs895819 polymorphisms were not significantly associated with lung cancer risks in any models.
|
26973201 |
2016 |
|
rs4919510
|
SEMA4G;MRPL43;MIR608
|
Carcinoma of lung
|
|
0.050 |
GeneticVariation |
BEFREE |
However, miR-196a2 rs11614913, miR-30c-1 rs928508, miR-608 rs4919510 and miR-27a rs895819 polymorphisms were not significantly associated with lung cancer risks in any models.
|
26973201 |
2016 |
|
rs4919510
|
SEMA4G;MRPL43;MIR608
|
Breast Carcinoma
|
|
0.050 |
GeneticVariation |
BEFREE |
Our data do not support an association of rs11614913:C > T and rs4919510:C > G with BC risk.
|
27421647 |
2016 |
|
rs4919510
|
SEMA4G;MRPL43;MIR608
|
Malignant neoplasm of lung
|
|
0.050 |
GeneticVariation |
BEFREE |
Our results showed that rs3746444 in mir-499 (allele C vs T: OR = 1.33; 95% CI = 1.15-1.54; P = 1.2 × 10-4) and rs4919510 in mir-608 (allele G vs C: OR = 1.27; 95% CI= 1.13-1.43; P = 5.1 × 10-5) were significantly associated with increased risk of lung cancer.
|
27232940 |
2016 |
|
rs4919510
|
SEMA4G;MRPL43;MIR608
|
Malignant neoplasm of breast
|
|
0.050 |
GeneticVariation |
BEFREE |
Our data do not support an association of rs11614913:C > T and rs4919510:C > G with BC risk.
|
27421647 |
2016 |
|
rs4919510
|
SEMA4G;MRPL43;MIR608
|
Primary malignant neoplasm of lung
|
|
0.050 |
GeneticVariation |
BEFREE |
Our results showed that rs3746444 in mir-499 (allele C vs T: OR = 1.33; 95% CI = 1.15-1.54; P = 1.2 × 10-4) and rs4919510 in mir-608 (allele G vs C: OR = 1.27; 95% CI= 1.13-1.43; P = 5.1 × 10-5) were significantly associated with increased risk of lung cancer.
|
27232940 |
2016 |
|
rs4919510
|
SEMA4G;MRPL43;MIR608
|
Malignant neoplasm of breast
|
|
0.050 |
GeneticVariation |
BEFREE |
In contrast, the miR-499 (rs3746444) AG/GG genotypes were associated with an increased risk of BC (OR = 1.45, 95% CI = 1.10-1.91), and miR-608 (rs4919510) was not significantly associated with BC risk.
|
26886638 |
2016 |
|
rs4919510
|
SEMA4G;MRPL43;MIR608
|
Carcinoma of lung
|
|
0.050 |
GeneticVariation |
BEFREE |
Our results showed that rs3746444 in mir-499 (allele C vs T: OR = 1.33; 95% CI = 1.15-1.54; P = 1.2 × 10-4) and rs4919510 in mir-608 (allele G vs C: OR = 1.27; 95% CI= 1.13-1.43; P = 5.1 × 10-5) were significantly associated with increased risk of lung cancer.
|
27232940 |
2016 |
|
rs4919510
|
SEMA4G;MRPL43;MIR608
|
Colorectal Carcinoma
|
|
0.050 |
GeneticVariation |
BEFREE |
The results showed that rs4919510</span> was significantly associated with a decreased susceptibility to CRC in co-dominant, allele and recessive genetic models, and the protective role of rs4919510 allele G and genotype GG was more pronounced among stage 0-II cases; significant association between rs531564 and poor RFS was observed in cases undergoing adjuvant chemo-radiotherapy in co-dominant, allele and dominant models; moreover, there was a positive association between rs7372209 and recurrence-free survival in stage II cases in co-dominant and over-dominant models; additionally, a cumulative effect of rs531564 and rs7372209 at-risk genotypes with hazard ratio at 1.30 and 1.95 for one and two at-risk genotypes was examined in stage II cases, respectively.
|
27713147 |
2016 |
|
rs4919510
|
SEMA4G;MRPL43;MIR608
|
Carcinoma of lung
|
|
0.050 |
GeneticVariation |
BEFREE |
The individuals with both risk genotypes of miRNA SNPs and exposure to risk factor (cooking oil fumes) were in a higher risk of lung cancer than persons with only one of the two risk factors (ORs were 1.91, 1.05 and 1.41 for miR-146a rs2910164, ORs were 1.94, 1.23 and 1.34 for miR-196a2 rs11614913, ORs were 2.06, 1.41 and 1.68 for miR-608 rs4919510, ORs were 1.76, 0.82 and 1.07 for miR-27a rs895819, and ORs were 2.13, 1.15 and 1.02 for miR-423 rs6505162, respectively).
|
26083623 |
2015 |