rs3816527
|
PTX3;VEPH1
|
Malignant Neoplasms
|
|
0.010 |
GeneticVariation |
BEFREE |
We found that rs3816527 in smokers was correlated with the development of late-stage cancer (odds ratio [OR], 2.328; 95% confidence interval [CI], 1.078-5.027) and increased lymph node metastasis (OR, 2.152; 95% CI, 1.047-4.422).
|
31334115 |
2019 |
rs3816527
|
PTX3;VEPH1
|
Malignant neoplasm of mouth
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, our results suggested that <i>PTX3</i> rs3816527 plays a role in oral cancer development.
|
31334115 |
2019 |
rs3816527
|
PTX3;VEPH1
|
Lip and Oral Cavity Carcinoma
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, our results suggested that <i>PTX3</i> rs3816527 plays a role in oral cancer development.
|
31334115 |
2019 |
rs3816527
|
PTX3;VEPH1
|
Primary malignant neoplasm
|
|
0.010 |
GeneticVariation |
BEFREE |
We found that rs3816527 in smokers was correlated with the development of late-stage cancer (odds ratio [OR], 2.328; 95% confidence interval [CI], 1.078-5.027) and increased lymph node metastasis (OR, 2.152; 95% CI, 1.047-4.422).
|
31334115 |
2019 |
rs3816527
|
PTX3;VEPH1
|
Secondary malignant neoplasm of lymph node
|
|
0.010 |
GeneticVariation |
BEFREE |
We found that rs3816527 in smokers was correlated with the development of late-stage cancer (odds ratio [OR], 2.328; 95% confidence interval [CI], 1.078-5.027) and increased lymph node metastasis (OR, 2.152; 95% CI, 1.047-4.422).
|
31334115 |
2019 |
rs1840680
|
PTX3;VEPH1
|
Bronchopulmonary Aspergillosis
|
|
0.010 |
GeneticVariation |
BEFREE |
This study showed a significant association between PTX3 rs1840680 polymorphisms and the susceptibility of pulmonary aspergillosis in patients with COPD.
|
29020397 |
2018 |
rs1840680
|
PTX3;VEPH1
|
Pulmonary Aspergillosis
|
|
0.010 |
GeneticVariation |
BEFREE |
This study showed a significant association between PTX3 rs1840680 polymorphisms and the susceptibility of pulmonary aspergillosis in patients with COPD.
|
29020397 |
2018 |
rs1840680
|
PTX3;VEPH1
|
Aphakia, congenital primary
|
|
0.010 |
GeneticVariation |
BEFREE |
The recessive model for SNP rs1840680 suggests that the AA homozygote is associated with a higher risk for pulmonary aspergillosis (both IPA and CPA) in COPD patients.
|
29020397 |
2018 |
rs1840680
|
PTX3;VEPH1
|
Incontinentia Pigmenti Achromians
|
|
0.010 |
GeneticVariation |
BEFREE |
The recessive model for SNP rs1840680 suggests that the AA homozygote is associated with a higher risk for pulmonary aspergillosis (both IPA and CPA) in COPD patients.
|
29020397 |
2018 |
rs1840680
|
PTX3;VEPH1
|
Aspergillosis
|
|
0.010 |
GeneticVariation |
BEFREE |
Three single nucleotide polymorphisms (SNPs; rs2305619, rs3816527, and rs1840680) in the PTX3 gene were detected by polymerase chain reaction direct sequencing, and their associations with aspergillosis were evaluated.
|
29020397 |
2018 |
rs1840680
|
PTX3;VEPH1
|
Chronic Obstructive Airway Disease
|
|
0.010 |
GeneticVariation |
BEFREE |
This study showed a significant association between PTX3 rs1840680 polymorphisms and the susceptibility of pulmonary aspergillosis in patients with COPD.
|
29020397 |
2018 |
rs2305619
|
PTX3;VEPH1
|
Diabetic Nephropathy
|
|
0.010 |
GeneticVariation |
BEFREE |
Patients with the GG variant of rs2305619 showed 4.078-fold higher susceptibility to DN than those with the AA variant (OR=4.078, 95% CI=1.370-12.135, p=0.012); patients with the AA variant of rs2120243 had a lower risk of developing DN (OR=0.213, 95% CI=0.055-0.826, p=0.025).
|
28119515 |
2017 |
rs3816527
|
PTX3;VEPH1
|
Chronic Kidney Diseases
|
|
0.010 |
GeneticVariation |
BEFREE |
Pentraxin 3 AA genotype SNP rs3816527 can be considered as a potential biomarker and a risk factor for CKD patients, especially hypertensive patients, and specifically as an independent predictor of hypertension in CKD.
|
27838804 |
2017 |
rs3816527
|
PTX3;VEPH1
|
Hypertensive disease
|
|
0.010 |
GeneticVariation |
BEFREE |
Pentraxin 3 AA genotype SNP rs3816527 can be considered as a potential biomarker and a risk factor for CKD patients, especially hypertensive patients, and specifically as an independent predictor of hypertension in CKD.
|
27838804 |
2017 |
rs2305619
|
PTX3;VEPH1
|
Liver carcinoma
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, PTX3 rs2305619 polymorphism and plasma levels were correlated with Child-Pugh scores B and C in HCC individuals.
|
26400151 |
2016 |
rs3816527
|
PTX3;VEPH1
|
Ankylosing spondylitis
|
|
0.010 |
GeneticVariation |
BEFREE |
RESULTS CC genotype of rs3816527 had an obviously higher frequency in cases than in controls and had a positive effect on AS occurrence (OR=3.14, 95%CI=1.04-9.52), and the same was true of the C allele in rs3816527.
|
27538101 |
2016 |
rs3845978
|
PTX3;VEPH1
|
Ankylosing spondylitis
|
|
0.010 |
GeneticVariation |
BEFREE |
For rs3845978, CT genotype showed a significant frequency difference between the case and control groups (P=0.03) and people with genotypes carrying the T allele developed AS earlier (OR=1.94, 95%CI=1.09-3.47), and the same was found in the analysis of the T allele.
|
27538101 |
2016 |
rs3816527
|
PTX3;VEPH1
|
Migraine Disorders
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion our results showed the association between the PTX3 rs3816527 gene polymorphism with susceptibility to migraine only in the male patients.
|
25604633 |
2015 |
rs2305619
|
PTX3;VEPH1
|
Idiopathic Pulmonary Fibrosis
|
|
0.010 |
GeneticVariation |
BEFREE |
The minor allele of rs2305619 was significantly associated with higher plasma PTX3 levels measured pretransplantation (P = 0.014) and at 24 hours (P = 0.047) after transplantation in patients with idiopathic pulmonary fibrosis.
|
22822025 |
2012 |
rs757818668
|
PTX3;VEPH1
|
Myocardial Infarction
|
|
0.010 |
GeneticVariation |
BEFREE |
The association of the D299G polymorphism of the TLR-4 gene with the progression of coronary and carotid atherosclerosis, risk of cardiovascular events and myocardial infarction is controversial.
|
15953129 |
2005 |
rs757818668
|
PTX3;VEPH1
|
Carotid Atherosclerosis
|
|
0.010 |
GeneticVariation |
BEFREE |
The presence of the D299G and T399I polymorphisms of the TLR-4 gene does not play a major role on the progression of carotid atherosclerosis.
|
15953129 |
2005 |