RAB5B, RAB5B, member RAS oncogene family, 5869

N. diseases: 22; N. variants: 10
Disease: Diabetes Mellitus, Insulin-Dependent ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs705699
rs705699
Entrez Id: 5869;6821
Gene Symbol: RAB5B;SUOX
RAB5B;SUOX
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		0.710 GeneticVariation BEFREE We identified four T1D risk loci reaching genome-wide significance in the Chinese Han population, including two novel loci, rs4320356 near <i>BTN3A1</i> (odds ratio [OR] 1.26, <i>P</i> = 2.70 × 10<sup>-8</sup>) and rs3802604 in <i>GATA3</i> (OR 1.24, <i>P</i> = 2.06 × 10<sup>-8</sup>), and two previously reported loci, rs1770 in MHC (OR 4.28, <i>P</i> = 2.25 × 10<sup>-232</sup>) and rs705699 in <i>SUOX</i> (OR 1.46, <i>P</i> = 7.48 × 10<sup>-20</sup>). 31152121 2019
dbSNP: rs705699
rs705699
Entrez Id: 5869;6821
Gene Symbol: RAB5B;SUOX
RAB5B;SUOX
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		T 0.710 GeneticVariation GWASCAT We identified four T1D risk loci reaching genome-wide significance in the Chinese Han population, including two novel loci, rs4320356 near <i>BTN3A1</i> (odds ratio [OR] 1.26, <i>P</i> = 2.70 × 10<sup>-8</sup>) and rs3802604 in <i>GATA3</i> (OR 1.24, <i>P</i> = 2.06 × 10<sup>-8</sup>), and two previously reported loci, rs1770 in MHC (OR 4.28, <i>P</i> = 2.25 × 10<sup>-232</sup>) and rs705699 in <i>SUOX</i> (OR 1.46, <i>P</i> = 7.48 × 10<sup>-20</sup>). 31152121 2019