RAD51C, RAD51 paralog C, 5889

N. diseases: 162; N. variants: 96
Disease: BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs387907159
rs387907159
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C3150659
Disease:
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 		T 0.700 CausalMutation CLINVAR Analysis of RAD51C germline mutations in high-risk breast and ovarian cancer families and ovarian cancer patients. 21990120 2012
dbSNP: rs387907159
rs387907159
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C3150659
Disease:
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 		T 0.700 CausalMutation CLINVAR Germline RAD51C mutations confer susceptibility to ovarian cancer. 22538716 2012
dbSNP: rs387907159
rs387907159
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C3150659
Disease:
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 		T 0.700 SusceptibilityMutation CLINVAR
dbSNP: rs587780259
rs587780259
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C3150659
Disease:
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 		G 0.700 CausalMutation CLINVAR Germline mutation in the RAD51B gene confers predisposition to breast cancer. 24139550 2013
dbSNP: rs587780259
rs587780259
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C3150659
Disease:
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 		G 0.700 CausalMutation CLINVAR Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population. 26261251 2015
dbSNP: rs587781287
rs587781287
Entrez Id: 5889;105371843
Gene Symbol: RAD51C;LOC105371843
RAD51C;LOC105371843
CUI: C3150659
Disease:
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 		T 0.700 CausalMutation CLINVAR
dbSNP: rs587781410
rs587781410
Entrez Id: 5889;105371843
Gene Symbol: RAD51C;LOC105371843
RAD51C;LOC105371843
CUI: C3150659
Disease:
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 		C 0.700 GeneticVariation CLINVAR Germline RAD51C mutations confer susceptibility to ovarian cancer. 22538716 2012
dbSNP: rs587781410
rs587781410
Entrez Id: 5889;105371843
Gene Symbol: RAD51C;LOC105371843
RAD51C;LOC105371843
CUI: C3150659
Disease:
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 		C 0.700 GeneticVariation CLINVAR Mutation Analysis of the RAD51C and RAD51D Genes in High-Risk Ovarian Cancer Patients and Families from the Czech Republic. 26057125 2015
dbSNP: rs587781410
rs587781410
Entrez Id: 5889;105371843
Gene Symbol: RAD51C;LOC105371843
RAD51C;LOC105371843
CUI: C3150659
Disease:
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 		C 0.700 GeneticVariation CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312 2016
dbSNP: rs587781410
rs587781410
Entrez Id: 5889;105371843
Gene Symbol: RAD51C;LOC105371843
RAD51C;LOC105371843
CUI: C3150659
Disease:
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 		C 0.700 GeneticVariation CLINVAR Germline mutation in the RAD51B gene confers predisposition to breast cancer. 24139550 2013
dbSNP: rs587781410
rs587781410
Entrez Id: 5889;105371843
Gene Symbol: RAD51C;LOC105371843
RAD51C;LOC105371843
CUI: C3150659
Disease:
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 		C 0.700 GeneticVariation CLINVAR Identification of functional domains in the RAD51L2 (RAD51C) protein and its requirement for gene conversion. 12966089 2003
dbSNP: rs587781410
rs587781410
Entrez Id: 5889;105371843
Gene Symbol: RAD51C;LOC105371843
RAD51C;LOC105371843
CUI: C3150659
Disease:
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 		C 0.700 CausalMutation CLINVAR
dbSNP: rs587781995
rs587781995
Entrez Id: 5889;105371843
Gene Symbol: RAD51C;LOC105371843
RAD51C;LOC105371843
CUI: C3150659
Disease:
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 		C 0.700 GeneticVariation CLINVAR Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population. 26261251 2015
dbSNP: rs587781995
rs587781995
Entrez Id: 5889;105371843
Gene Symbol: RAD51C;LOC105371843
RAD51C;LOC105371843
CUI: C3150659
Disease:
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 		C 0.700 GeneticVariation CLINVAR Hereditary truncating mutations of DNA repair and other genes in BRCA1/BRCA2/PALB2-negatively tested breast cancer patients. 26822949 2016
dbSNP: rs587782036
rs587782036
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C3150659
Disease:
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 		C 0.700 GeneticVariation CLINVAR
dbSNP: rs587782528
rs587782528
Entrez Id: 5889;56155
Gene Symbol: RAD51C;TEX14
RAD51C;TEX14
CUI: C3150659
Disease:
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 		T 0.700 CausalMutation CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312 2016
dbSNP: rs587782528
rs587782528
Entrez Id: 5889;56155
Gene Symbol: RAD51C;TEX14
RAD51C;TEX14
CUI: C3150659
Disease:
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 		T 0.700 CausalMutation CLINVAR Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population. 26261251 2015
dbSNP: rs587782528
rs587782528
Entrez Id: 5889;56155
Gene Symbol: RAD51C;TEX14
RAD51C;TEX14
CUI: C3150659
Disease:
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 		T 0.700 CausalMutation CLINVAR Patterns and functional implications of rare germline variants across 12 cancer types. 26689913 2015
dbSNP: rs587782702
rs587782702
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C3150659
Disease:
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 		T 0.700 SusceptibilityMutation CLINVAR
dbSNP: rs587782818
rs587782818
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C3150659
Disease:
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 		G 0.700 CausalMutation CLINVAR
dbSNP: rs730881931
rs730881931
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C3150659
Disease:
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 		C 0.700 GeneticVariation CLINVAR
dbSNP: rs730881939
rs730881939
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C3150659
Disease:
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 		TA 0.700 CausalMutation CLINVAR Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene. 20400964 2010
dbSNP: rs730881939
rs730881939
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C3150659
Disease:
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 		TA 0.700 CausalMutation CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312 2016
dbSNP: rs730881939
rs730881939
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C3150659
Disease:
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 		TA 0.700 CausalMutation CLINVAR Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing. 22006311 2011
dbSNP: rs730881942
rs730881942
Entrez Id: 5889;56155
Gene Symbol: RAD51C;TEX14
RAD51C;TEX14
CUI: C3150659
Disease:
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 		C 0.700 SusceptibilityMutation CLINVAR