RAD51C, RAD51 paralog C, 5889

N. diseases: 162; N. variants: 96
Disease: Neoplastic Syndromes, Hereditary ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs200293302
rs200293302
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 CausalMutation CLINVAR Secondary Somatic Mutations Restoring RAD51C and RAD51D Associated with Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma. 28588062 2017
dbSNP: rs200293302
rs200293302
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 CausalMutation CLINVAR Identification of six pathogenic RAD51C mutations via mutational screening of 1228 Danish individuals with increased risk of hereditary breast and/or ovarian cancer. 26740214 2016
dbSNP: rs200293302
rs200293302
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 CausalMutation CLINVAR Genetic testing for RAD51C mutations: in the clinic and community. 25470109 2015
dbSNP: rs200293302
rs200293302
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 CausalMutation CLINVAR Germline and somatic mutations in homologous recombination genes predict platinum response and survival in ovarian, fallopian tube, and peritoneal carcinomas. 24240112 2014
dbSNP: rs200293302
rs200293302
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 CausalMutation CLINVAR RAD51C germline mutations found in Spanish site-specific breast cancer and breast-ovarian cancer families. 25086635 2014
dbSNP: rs200293302
rs200293302
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 CausalMutation CLINVAR Germline RAD51C mutations in ovarian cancer susceptibility. 22725699 2013
dbSNP: rs200293302
rs200293302
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 CausalMutation CLINVAR Germline mutations in RAD51C in Jewish high cancer risk families. 23117857 2012
dbSNP: rs200293302
rs200293302
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 CausalMutation CLINVAR Germline RAD51C mutations confer susceptibility to ovarian cancer. 22538716 2012