RAD51C, RAD51 paralog C, 5889

N. diseases: 162; N. variants: 96
Disease: Neoplastic Syndromes, Hereditary ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs730881939
rs730881939
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		TA 0.700 CausalMutation CLINVAR Veliparib Alone or in Combination with Mitomycin C in Patients with Solid Tumors With Functional Deficiency in Homologous Recombination Repair. 26848151 2016
dbSNP: rs730881939
rs730881939
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		TA 0.700 CausalMutation CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312 2016
dbSNP: rs730881939
rs730881939
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		TA 0.700 CausalMutation CLINVAR Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing. 22006311 2011
dbSNP: rs730881939
rs730881939
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		TA 0.700 CausalMutation CLINVAR Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene. 20400964 2010