RAD51C, RAD51 paralog C, 5889

N. diseases: 162; N. variants: 96
Disease: Hereditary Breast and Ovarian Cancer Syndrome ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs200293302
rs200293302
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C0677776
Disease:
Hereditary Breast and Ovarian Cancer Syndrome 		T 0.700 CausalMutation CLINVAR Identification of six pathogenic RAD51C mutations via mutational screening of 1228 Danish individuals with increased risk of hereditary breast and/or ovarian cancer. 26740214 2016
dbSNP: rs200293302
rs200293302
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C0677776
Disease:
Hereditary Breast and Ovarian Cancer Syndrome 		T 0.700 CausalMutation CLINVAR Frequency of Germline Mutations in 25 Cancer Susceptibility Genes in a Sequential Series of Patients With Breast Cancer. 26976419 2016
dbSNP: rs200293302
rs200293302
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C0677776
Disease:
Hereditary Breast and Ovarian Cancer Syndrome 		T 0.700 CausalMutation CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312 2016
dbSNP: rs200293302
rs200293302
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C0677776
Disease:
Hereditary Breast and Ovarian Cancer Syndrome 		T 0.700 CausalMutation CLINVAR RAD51C germline mutations found in Spanish site-specific breast cancer and breast-ovarian cancer families. 25086635 2014
dbSNP: rs200293302
rs200293302
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C0677776
Disease:
Hereditary Breast and Ovarian Cancer Syndrome 		T 0.700 CausalMutation CLINVAR Germline RAD51C mutations confer susceptibility to ovarian cancer. 22538716 2012