RAD51C, RAD51 paralog C, 5889

N. diseases: 162; N. variants: 96
Disease: Hereditary Breast and Ovarian Cancer Syndrome ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs730881939
rs730881939
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C0677776
Disease:
Hereditary Breast and Ovarian Cancer Syndrome 		TA 0.700 CausalMutation CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312 2016
dbSNP: rs730881939
rs730881939
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C0677776
Disease:
Hereditary Breast and Ovarian Cancer Syndrome 		TA 0.700 CausalMutation CLINVAR RPA and Rad51 constitute a cell intrinsic mechanism to protect the cytosol from self DNA. 27230542 2016
dbSNP: rs730881939
rs730881939
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C0677776
Disease:
Hereditary Breast and Ovarian Cancer Syndrome 		TA 0.700 CausalMutation CLINVAR Veliparib Alone or in Combination with Mitomycin C in Patients with Solid Tumors With Functional Deficiency in Homologous Recombination Repair. 26848151 2016
dbSNP: rs730881939
rs730881939
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
CUI: C0677776
Disease:
Hereditary Breast and Ovarian Cancer Syndrome 		TA 0.700 CausalMutation CLINVAR Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene. 20400964 2010