rs267606997
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
FANCONI ANEMIA, COMPLEMENTATION GROUP O
A
0.800
GeneticVariation
CLINVAR
Mammalian RAD51 paralogs protect nascent DNA at stalled forks and mediate replication restart.
26354865
2015
rs267606997
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
FANCONI ANEMIA, COMPLEMENTATION GROUP O
0.800
GeneticVariation
UNIPROT
Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair.
24141787
2014
rs267606998
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
0.800
GeneticVariation
UNIPROT
Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair.
24141787
2014
rs267606999
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
C
0.800
GeneticVariation
CLINVAR
Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair.
24141787
2014
rs267606999
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
0.800
GeneticVariation
UNIPROT
Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair.
24141787
2014
rs267606997
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
FANCONI ANEMIA, COMPLEMENTATION GROUP O
A
0.800
GeneticVariation
CLINVAR
Distinct roles of FANCO/RAD51C protein in DNA damage signaling and repair: implications for Fanconi anemia and breast cancer susceptibility.
22167183
2012
rs267606998
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
0.800
GeneticVariation
UNIPROT
Analysis of RAD51C germline mutations in high-risk breast and ovarian cancer families and ovarian cancer patients.
21990120
2012
rs267606999
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
C
0.800
GeneticVariation
CLINVAR
Distinct roles of FANCO/RAD51C protein in DNA damage signaling and repair: implications for Fanconi anemia and breast cancer susceptibility.
22167183
2012
rs267606999
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
0.800
GeneticVariation
UNIPROT
Analysis of RAD51C germline mutations in high-risk breast and ovarian cancer families and ovarian cancer patients.
21990120
2012
rs267606999
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
C
0.800
GeneticVariation
CLINVAR
Germline RAD51C mutations confer susceptibility to ovarian cancer.
22538716
2012
rs267606999
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
C
0.800
GeneticVariation
CLINVAR
Predominance of pathogenic missense variants in the RAD51C gene occurring in breast and ovarian cancer families.
22451500
2012
rs267606997
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
FANCONI ANEMIA, COMPLEMENTATION GROUP O
A
0.800
GeneticVariation
CLINVAR
Mutation of the RAD51C gene in a Fanconi anemia-like disorder.
20400963
2010
rs267606997
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
FANCONI ANEMIA, COMPLEMENTATION GROUP O
0.800
GeneticVariation
UNIPROT
Mutation of the RAD51C gene in a Fanconi anemia-like disorder.
20400963
2010
rs267606998
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
0.800
GeneticVariation
UNIPROT
Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene.
20400964
2010
rs267606999
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
C
0.800
GeneticVariation
CLINVAR
Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene.
20400964
2010
rs267606999
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
0.800
GeneticVariation
UNIPROT
Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene.
20400964
2010
rs267606997
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
FANCONI ANEMIA, COMPLEMENTATION GROUP O
A
0.800
CausalMutation
CLINVAR
rs267606998
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
T
0.800
SusceptibilityMutation
CLINVAR
rs267606999
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
C
0.800
SusceptibilityMutation
CLINVAR
rs1327086366
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
Hereditary Breast and Ovarian Cancer Syndrome
A
0.700
GeneticVariation
CLINVAR
Association Between Inherited Germline Mutations in Cancer Predisposition Genes and Risk of Pancreatic Cancer.
29922827
2018
rs387907159
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
Hereditary Breast and Ovarian Cancer Syndrome
T
0.700
CausalMutation
CLINVAR
Association Between Inherited Germline Mutations in Cancer Predisposition Genes and Risk of Pancreatic Cancer.
29922827
2018
rs767796996
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
Hereditary Breast and Ovarian Cancer Syndrome
A
0.700
GeneticVariation
CLINVAR
Mutational analysis of RAD51C and RAD51D genes in hereditary breast and ovarian cancer families from Murcia (southeastern Spain).
29409816
2018
rs1555605074
RAD51C;LOC105371843
Neoplastic Syndromes, Hereditary
T
0.700
GeneticVariation
CLINVAR
Gene panel sequencing in familial breast/ovarian cancer patients identifies multiple novel mutations also in genes others than BRCA1/2.
27616075
2017
rs1555605074
RAD51C;LOC105371843
FANCONI ANEMIA, COMPLEMENTATION GROUP O
T
0.700
GeneticVariation
CLINVAR
Gene panel sequencing in familial breast/ovarian cancer patients identifies multiple novel mutations also in genes others than BRCA1/2.
27616075
2017
rs200293302
×
Entrez Id:
5889
Gene Symbol:
RAD51C
RAD51C
Neoplastic Syndromes, Hereditary
T
0.700
CausalMutation
CLINVAR
Secondary Somatic Mutations Restoring RAD51C and RAD51D Associated with Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma.
28588062
2017