RAD51B, RAD51 paralog B, 5890

N. diseases: 126; N. variants: 108
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1314913
rs1314913
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B
CUI: C0678222
Disease:
Breast Carcinoma 		0.830 GeneticVariation BEFREE In our study, we evaluted the relation between DNA repair gene polymorphisms XRCC1 rs1799782, rs25487, rs25489; XPC rs2228000, rs2228001; XPD rs1799793, rs13181; XRCC3 rs861539; RAD51B rs10483813, rs1314913 and breast cancer risk for 202 Turkish cases in total, in which 102 patients with breast cancer and 100 controls. 28983784 2019
dbSNP: rs8017304
rs8017304
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B
CUI: C0242383
Disease:
Age related macular degeneration 		0.830 GeneticVariation BEFREE <i>RAD51B</i> (rs8017304 and rs2588809), <i>TRIB1</i> (rs6987702, rs4351379, and rs4351376), <i>COL8A1</i> (rs13095226), and <i>COL10A1</i> (rs1064583) Gene Variants with Predisposition to Age-Related Macular Degeneration. 31191752 2019
dbSNP: rs8017304
rs8017304
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B
CUI: C0242383
Disease:
Age related macular degeneration 		0.830 GeneticVariation BEFREE Nineteen single nucleotide polymorphisms (SNPs) previously associated with AMD, including rs10490924 (<i>ARMS2/HTRA1</i>), rs10737680 (<i>CFH</i>), rs13278062 (<i>TNFRSF10A</i>), rs1864163 (<i>CETP</i>), rs2230199 (<i>C3</i>), rs3130783 (<i>IER3/DDR1</i>), rs334353 (<i>TGFBR1</i>), rs3812111 (<i>COL10A1</i>), rs429608 (<i>C2/CFB</i>), rs4420638 (<i>APOE</i>), rs4698775 (<i>CFI</i>), rs5749482 (<i>TIMP3</i>), rs6795735 (<i>ADAMTS9</i>), rs8017304 (<i>RAD51B</i>), rs8135665 (<i>SLC16A8</i>), rs920915 (<i>LIPC</i>), rs943080 (<i>VEGFA</i>), rs9542236 (<i>B3GALTL</i>) and rs13081855 (<i>COL8A1/FILIP1L</i>), were genotyped in this cohort. 31819893 2019
dbSNP: rs1314913
rs1314913
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B
CUI: C0678222
Disease:
Breast Carcinoma 		0.830 GeneticVariation BEFREE Common variation on 14q24.1, close to RAD51B, has been associated with breast cancer: rs999737 and rs2588809 with the risk of female breast cancer and rs1314913 with the risk of male breast cancer. 27149063 2016
dbSNP: rs1314913
rs1314913
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B
CUI: C0678222
Disease:
Breast Carcinoma 		0.830 GeneticVariation BEFREE Furthermore, we showed that the SNPs rs1562430/8q24.21 and rs1314913/14q24.1 strongly influence BC risk in men and suggested that the SNP rs1314913/14q24.1 may act as a risk modifier locus in male BRCA1/2 mutation carriers. 26248686 2015
dbSNP: rs8017304
rs8017304
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B
CUI: C0242383
Disease:
Age related macular degeneration 		0.830 GeneticVariation BEFREE The Caucasian set replicated the rs8017304 A>G association and revealed two novel AMD-associated SNPs in RAD51B, rs17105278 T>C and rs4902566 C>T. 24526414 2014
dbSNP: rs8017304
rs8017304
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B
CUI: C0242383
Disease:
Age related macular degeneration 		A 0.830 GeneticVariation GWASCAT Seven new loci associated with age-related macular degeneration. 23455636 2013
dbSNP: rs8017304
rs8017304
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B
CUI: C0242383
Disease:
Age related macular degeneration 		0.830 GeneticVariation GWASDB Seven new loci associated with age-related macular degeneration. 23455636 2013
dbSNP: rs1314913
rs1314913
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B
CUI: C0678222
Disease:
Breast Carcinoma 		0.830 GeneticVariation GWASCAT Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk. 23001122 2012
dbSNP: rs1314913
rs1314913
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B
CUI: C0678222
Disease:
Breast Carcinoma 		0.830 GeneticVariation GWASDB Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk. 23001122 2012
dbSNP: rs2588809
rs2588809
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B
CUI: C0678222
Disease:
Breast Carcinoma 		T 0.820 GeneticVariation GWASCAT Association analysis identifies 65 new breast cancer risk loci. 29059683 2017
dbSNP: rs2588809
rs2588809
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B
CUI: C0678222
Disease:
Breast Carcinoma 		0.820 GeneticVariation BEFREE Common variation on 14q24.1, close to RAD51B, has been associated with breast cancer: rs999737 and rs2588809 with the risk of female breast cancer and rs1314913 with the risk of male breast cancer. 27149063 2016
dbSNP: rs2588809
rs2588809
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B
CUI: C0678222
Disease:
Breast Carcinoma 		0.820 GeneticVariation BEFREE We observed a significant inverse association (P=8.75 × 10(-6); FDR=0.001) between the risk allele in rs2588809 of the gene RAD51B and TSMC across all breast cancer patients, for both ER(+) and ER(-) tumours. 27467053 2016
dbSNP: rs2588809
rs2588809
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B
CUI: C0678222
Disease:
Breast Carcinoma 		T 0.820 GeneticVariation GWASCAT Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer. 25751625 2015
dbSNP: rs2588809
rs2588809
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B
CUI: C0678222
Disease:
Breast Carcinoma 		T 0.820 GeneticVariation GWASCAT Large-scale genotyping identifies 41 new loci associated with breast cancer risk. 23535729 2013
dbSNP: rs2588809
rs2588809
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B
CUI: C0678222
Disease:
Breast Carcinoma 		0.820 GeneticVariation GWASDB Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk. 23001122 2012
dbSNP: rs1950897
rs1950897
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B
CUI: C0003873
Disease:
Rheumatoid Arthritis 		T 0.800 GeneticVariation GWASCAT Genetic influences on susceptibility to rheumatoid arthritis in African-Americans. 30423114 2019
dbSNP: rs1744947
rs1744947
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B
CUI: C0678222
Disease:
Breast Carcinoma 		T 0.800 GeneticVariation GWASCAT Association analysis identifies 65 new breast cancer risk loci. 29059683 2017
dbSNP: rs911263
rs911263
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B
CUI: C0008312
Disease:
Primary biliary cirrhosis 		T 0.800 GeneticVariation GWASCAT International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways. 26394269 2015
dbSNP: rs1950897
rs1950897
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B
CUI: C0003873
Disease:
Rheumatoid Arthritis 		T 0.800 GeneticVariation GWASDB Genetics of rheumatoid arthritis contributes to biology and drug discovery. 24390342 2014
dbSNP: rs1950897
rs1950897
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B
CUI: C0003873
Disease:
Rheumatoid Arthritis 		T 0.800 GeneticVariation GWASCAT Genetics of rheumatoid arthritis contributes to biology and drug discovery. 24390342 2014
dbSNP: rs1744947
rs1744947
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B
CUI: C0678222
Disease:
Breast Carcinoma 		0.800 GeneticVariation GWASDB Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk. 23001122 2012
dbSNP: rs911263
rs911263
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B
CUI: C0008312
Disease:
Primary biliary cirrhosis 		0.800 GeneticVariation GWASDB Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis. 22961000 2012
dbSNP: rs911263
rs911263
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B
CUI: C0008312
Disease:
Primary biliary cirrhosis 		A 0.800 GeneticVariation GWASCAT Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis. 22961000 2012
dbSNP: rs8022206
rs8022206
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B
CUI: C0032181
Disease:
Platelet Count measurement 		G 0.800 GeneticVariation GWASDB New gene functions in megakaryopoiesis and platelet formation. 22139419 2011