rs121917743
×
Entrez Id:
5972
Gene Symbol:
REN
REN
Hyperuricemic Nephropathy, Familial Juvenile 2
0.800
GeneticVariation
UNIPROT
Dominant renin gene mutations associated with early-onset hyperuricemia, anemia, and chronic kidney failure.
19664745
2009
rs121917742
×
Entrez Id:
5972
Gene Symbol:
REN
REN
Allanson Pantzar McLeod syndrome
0.800
GeneticVariation
UNIPROT
Mutations in genes in the renin-angiotensin system are associated with autosomal recessive renal tubular dysgenesis.
16116425
2005
rs121917742
×
Entrez Id:
5972
Gene Symbol:
REN
REN
Allanson Pantzar McLeod syndrome
T
0.800
CausalMutation
CLINVAR
rs121917743
×
Entrez Id:
5972
Gene Symbol:
REN
REN
Hyperuricemic Nephropathy, Familial Juvenile 2
T
0.800
GeneticVariation
CLINVAR
rs121917743
×
Entrez Id:
5972
Gene Symbol:
REN
REN
Hyperuricemic Nephropathy, Familial Juvenile 2
C
0.800
CausalMutation
CLINVAR
rs72749713
×
Entrez Id:
5972
Gene Symbol:
REN
REN
Systolic Pressure
0.700
GeneticVariation
GWASCAT
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
30595370
2019
rs193280350
×
Entrez Id:
5972
Gene Symbol:
REN
REN
Blood Protein Measurement
A
0.700
GeneticVariation
GWASCAT
Genomic atlas of the human plasma proteome.
29875488
2018
rs12040249
×
Entrez Id:
5972
Gene Symbol:
REN
REN
Leukemia, Myelocytic, Acute
G
0.700
GeneticVariation
GWASCAT
Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.
27903959
2017
rs11571111
×
Entrez Id:
5972
Gene Symbol:
REN
REN
Serum HDL cholesterol measurement
0.700
GeneticVariation
GWASDB
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
23063622
2012
rs11571111
×
Entrez Id:
5972
Gene Symbol:
REN
REN
Triglycerides measurement
0.700
GeneticVariation
GWASDB
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
23063622
2012
rs11571111
×
Entrez Id:
5972
Gene Symbol:
REN
REN
High density lipoprotein measurement
0.700
GeneticVariation
GWASDB
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
23063622
2012
rs11571111
×
Entrez Id:
5972
Gene Symbol:
REN
REN
Serum total cholesterol measurement
0.700
GeneticVariation
GWASDB
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
23063622
2012
rs6668858
×
Entrez Id:
5972
Gene Symbol:
REN
REN
High density lipoprotein measurement
0.700
GeneticVariation
GWASDB
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
23063622
2012
rs6668858
×
Entrez Id:
5972
Gene Symbol:
REN
REN
Serum HDL cholesterol measurement
0.700
GeneticVariation
GWASDB
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
23063622
2012
rs6668858
×
Entrez Id:
5972
Gene Symbol:
REN
REN
Triglycerides measurement
0.700
GeneticVariation
GWASDB
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
23063622
2012
rs6668858
×
Entrez Id:
5972
Gene Symbol:
REN
REN
Serum total cholesterol measurement
0.700
GeneticVariation
GWASDB
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
23063622
2012
rs121917740
×
Entrez Id:
5972
Gene Symbol:
REN
REN
HYPERPRORENINEMIA, FAMILIAL
A
0.700
CausalMutation
CLINVAR
rs121917741
×
Entrez Id:
5972
Gene Symbol:
REN
REN
Allanson Pantzar McLeod syndrome
A
0.700
CausalMutation
CLINVAR
rs397514690
×
Entrez Id:
5972
Gene Symbol:
REN
REN
Allanson Pantzar McLeod syndrome
A
0.700
CausalMutation
CLINVAR
rs397514691
×
Entrez Id:
5972
Gene Symbol:
REN
REN
Allanson Pantzar McLeod syndrome
T
0.700
CausalMutation
CLINVAR
rs868694193
×
Entrez Id:
5972
Gene Symbol:
REN
REN
Allanson Pantzar McLeod syndrome
0.700
GeneticVariation
UNIPROT
rs777208537
×
Entrez Id:
5972
Gene Symbol:
REN
REN
Hypertensive disease
0.030
GeneticVariation
BEFREE
In addition to these polymorphisms, the T(-344)C polymorphism in the promoter of the aldosterone synthase gene (CYP11B2) and the C825T polymorphism of the G-protein beta3 subunit gene (GNB3) are considered candidates for the genetic risk of salt-sensitive hypertension .
12924618
2003
rs777208537
×
Entrez Id:
5972
Gene Symbol:
REN
REN
Hypertensive disease
0.030
GeneticVariation
BEFREE
A functional single-nucleotide variant of the gene encoding the beta3 subunit of heterotrimeric G proteins (Gbeta3 C825T ), associated with enhanced G-protein activation and increased activity of the sodium-proton exchanger (NHE1), has been implicated in the development of hypertension .
10930182
2000
rs777208537
×
Entrez Id:
5972
Gene Symbol:
REN
REN
Hypertensive disease
0.030
GeneticVariation
BEFREE
Association between the C825T polymorphism of the G protein beta3-subunit gene and hypertension in blacks.
10601117
1999
rs2368564
×
Entrez Id:
5972
Gene Symbol:
REN
REN
Essential Hypertension
0.010
GeneticVariation
BEFREE
The genotypic and allelic distributions of rs2368564 in essential hypertension and control was significant statistically ( p<0.001).
29233044
2018