rs79658334
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
T
0.720
CausalMutation
CLINVAR
Revised American Thyroid Association guidelines for the management of medullary thyroid carcinoma.
25810047
2015
rs79658334
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
0.720
GeneticVariation
BEFREE
A NOVEL DOUBLE MUTATION VAL648ILE AND VAL804LEU OF RET PROTO-ONCOGENE IN MULTIPLE ENDOCRINE NEOPLASIA TYPE 2 .
26247112
2015
rs79658334
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
A
0.720
CausalMutation
CLINVAR
Characterization of V804M-mutated RET proto-oncogene associated with familial medullary thyroid cancer, report of the largest Turkish family.
25501606
2015
rs79658334
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
A
0.720
CausalMutation
CLINVAR
Revised American Thyroid Association guidelines for the management of medullary thyroid carcinoma.
25810047
2015
rs79658334
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
A
0.720
CausalMutation
CLINVAR
Twenty years of lesson learning: how does the RET genetic screening test impact the clinical management of medullary thyroid cancer?
25440022
2015
rs79658334
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
T
0.720
CausalMutation
CLINVAR
Identification of Novel Small Molecule Inhibitors of Oncogenic RET Kinase.
26046350
2015
rs79658334
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
A
0.720
CausalMutation
CLINVAR
Patient affected by neurofibromatosis type 1 and thyroid C-cell hyperplasia harboring pathogenic germ-line mutations in both NF1 and RET genes.
24361808
2014
rs79658334
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
A
0.720
CausalMutation
CLINVAR
Prevalence by age and predictors of medullary thyroid cancer in patients with lower risk germline RET proto-oncogene mutations.
24617864
2014
rs79658334
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
A
0.720
CausalMutation
CLINVAR
Tandem Germline RET Mutations in a Family Pathogenetic for Multiple Endocrine Neoplasia 2B, Confirmed by a Natural Experiment.
25759805
2014
rs79658334
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
A
0.720
CausalMutation
CLINVAR
Novel tandem germline RET proto-oncogene mutations in a patient with multiple endocrine neoplasia type 2B: report of a case and a literature review of tandem RET mutations with in silico analysis.
23468374
2013
rs79658334
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
A
0.720
CausalMutation
CLINVAR
RET codon 804 mutations in multiple endocrine neoplasia 2: genotype-phenotype correlations and implications in clinical management.
20497437
2011
rs79658334
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
A
0.720
CausalMutation
CLINVAR
Germline RET sequence variation I852M and occult medullary thyroid cancer: harmless polymorphism or causative mutation?
21711375
2011
rs79658334
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
T
0.720
CausalMutation
CLINVAR
RET codon 804 mutations in multiple endocrine neoplasia 2: genotype-phenotype correlations and implications in clinical management.
20497437
2011
rs79658334
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
A
0.720
CausalMutation
CLINVAR
Single nucleotide polymorphisms act as modifiers and correlate with the development of medullary and simultaneous medullary/papillary thyroid carcinomas in 2 large, non-related families with the RET V804M proto-oncogene mutation.
21134561
2010
rs79658334
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
A
0.720
CausalMutation
CLINVAR
A novel de novo germ-line V292M mutation in the extracellular region of RET in a patient with phaeochromocytoma and medullary thyroid carcinoma: functional characterization.
20039896
2010
rs79658334
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
A
0.720
CausalMutation
CLINVAR
One hundred and seven family members with the rearranged during transfection V804M proto-oncogene mutation presenting with simultaneous medullary and papillary thyroid carcinomas, rare primary hyperparathyroidism, and no pheochromocytomas: is this a new syndrome--MEN 2C?
19958926
2009
rs79658334
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
A
0.720
CausalMutation
CLINVAR
Familial medullary thyroid carcinoma associated with cutaneous lichen amyloidosis.
19445625
2009
rs79658334
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
A
0.720
CausalMutation
CLINVAR
RET proto-oncogene in Sardinia: V804M is the most frequent mutation and may be associated with FMTC/MEN-2A phenotype.
17316110
2007
rs79658334
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
A
0.720
CausalMutation
CLINVAR
RET genetic screening in patients with medullary thyroid cancer and their relatives: experience with 807 individuals at one center.
17895320
2007
rs79658334
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
A
0.720
CausalMutation
CLINVAR
Asymptomatic bilateral adrenal pheochromocytoma in a patient with a germline V804M mutation in the RET proto-oncogene.
17466010
2007
rs79658334
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
T
0.720
CausalMutation
CLINVAR
BAY 43-9006 inhibition of oncogenic RET mutants.
16507829
2006
rs79658334
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
T
0.720
CausalMutation
CLINVAR
New era: prophylactic surgery for patients with multiple endocrine neoplasia-2a.
16813623
2006
rs79658334
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
0.720
GeneticVariation
BEFREE
Some studies have suggested that the V804L mutation causes the low penetrance multiple endocrine neoplasia type 2 syndrome, with late onset and relatively indolent course, whereas others have reported that V804L and V804M have an aggressive potential.
15741265
2005
rs79658334
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
T
0.720
CausalMutation
CLINVAR
Experience of prophylactic thyroidectomy in multiple endocrine neoplasia type 2A kindreds with RET codon 804 mutations.
16343097
2005
rs79658334
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
A
0.720
CausalMutation
CLINVAR
Some studies have suggested that the V804L mutation causes the low penetrance multiple endocrine neoplasia type 2 syndrome, with late onset and relatively indolent course, whereas others have reported that V804L and V804M have an aggressive potential.
15741265
2005