DisGeNET - a database of gene-disease associations

REV3L, REV3 like, DNA directed polymerase zeta catalytic subunit, 5980

N. diseases: 95; N. variants: 94

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs240993

Entrez Id:	5980;91749
Gene Symbol:	REV3L;MFSD4B

REV3L;MFSD4B

CUI:	C0033860
Disease:

Psoriasis

0.800

GeneticVariation

GWASCAT

Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms.

25574825

2015

dbSNP:

rs240993

Entrez Id:	5980;91749
Gene Symbol:	REV3L;MFSD4B

REV3L;MFSD4B

CUI:	C0033860
Disease:

Psoriasis

0.800

GeneticVariation

GWASCAT

Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility.

25903422

2015

dbSNP:

rs465969

Entrez Id:	5980;91749
Gene Symbol:	REV3L;MFSD4B

REV3L;MFSD4B

CUI:	C0033860
Disease:

Psoriasis

0.800

GeneticVariation

GWASCAT

Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms.

25574825

2015

dbSNP:

rs240993

Entrez Id:	5980;91749
Gene Symbol:	REV3L;MFSD4B

REV3L;MFSD4B

CUI:	C0033860
Disease:

Psoriasis

0.800

GeneticVariation

GWASDB

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

20953190

2010

dbSNP:

rs240993

Entrez Id:	5980;91749
Gene Symbol:	REV3L;MFSD4B

REV3L;MFSD4B

CUI:	C0033860
Disease:

Psoriasis

0.800

GeneticVariation

GWASCAT

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

20953190

2010

dbSNP:

rs458017

Entrez Id:	5980;91749
Gene Symbol:	REV3L;MFSD4B

REV3L;MFSD4B

CUI:	C0033860
Disease:

Psoriasis

0.800

GeneticVariation

GWASCAT

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

20953190

2010

dbSNP:

rs458017

Entrez Id:	5980;91749
Gene Symbol:	REV3L;MFSD4B

REV3L;MFSD4B

CUI:	C0033860
Disease:

Psoriasis

0.800

GeneticVariation

GWASDB

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

20953190

2010

dbSNP:

rs465969

Entrez Id:	5980;91749
Gene Symbol:	REV3L;MFSD4B

REV3L;MFSD4B

CUI:	C0033860
Disease:

Psoriasis

0.800

GeneticVariation

GWASDB

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

20953190

2010

dbSNP:

rs240955

Entrez Id:	5980;91749
Gene Symbol:	REV3L;MFSD4B

REV3L;MFSD4B

CUI:	C0037369
Disease:

Smoking

0.700

GeneticVariation

GWASCAT

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.

30643258

2019

dbSNP:

rs458017

Entrez Id:	5980;91749
Gene Symbol:	REV3L;MFSD4B

REV3L;MFSD4B

CUI:	C0003872
Disease:

Arthritis, Psoriatic

0.700

GeneticVariation

GWASCAT

Genetic variation at the glycosaminoglycan metabolism pathway contributes to the risk of psoriatic arthritis but not psoriasis.

30552173

2019

dbSNP:

rs71562294

Entrez Id:	5980;643749
Gene Symbol:	REV3L;TRAF3IP2-AS1

REV3L;TRAF3IP2-AS1

CUI:	C0003872
Disease:

Arthritis, Psoriatic

0.700

GeneticVariation

GWASCAT

Genetic variation at the glycosaminoglycan metabolism pathway contributes to the risk of psoriatic arthritis but not psoriasis.

30552173

2019

dbSNP:

rs17072594

Entrez Id:	5980;91749
Gene Symbol:	REV3L;MFSD4B

REV3L;MFSD4B

CUI:	C0410702
Disease:

Adolescent idiopathic scoliosis

0.700

GeneticVariation

GWASCAT

The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

30019117

2018

dbSNP:

rs17072594

Entrez Id:	5980;91749
Gene Symbol:	REV3L;MFSD4B

REV3L;MFSD4B

CUI:	C1837461
Disease:

SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3

0.700

GeneticVariation

GWASCAT

The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

30019117

2018

dbSNP:

rs1057519367

Entrez Id:	5980;91749
Gene Symbol:	REV3L;MFSD4B

REV3L;MFSD4B

CUI:	C0009402
Disease:

Colorectal Carcinoma

0.700

GeneticVariation

CLINVAR

The Fanconi anemia DNA damage repair pathway in the spotlight for germline predisposition to colorectal cancer.

27165003

2016

dbSNP:

rs1002475

Entrez Id:	5980;91749
Gene Symbol:	REV3L;MFSD4B

REV3L;MFSD4B

CUI:	C0523465
Disease:

Serum albumin measurement

0.700

GeneticVariation

GWASDB

Genome-wide association study identifies multiple loci influencing human serum metabolite levels.

22286219

2012

dbSNP:

rs10456875

Entrez Id:	5980;91749
Gene Symbol:	REV3L;MFSD4B

REV3L;MFSD4B

CUI:	C0523465
Disease:

Serum albumin measurement

0.700

GeneticVariation

GWASDB

Genome-wide association study identifies multiple loci influencing human serum metabolite levels.

22286219

2012

dbSNP:

rs10457238

Entrez Id:	5980;91749
Gene Symbol:	REV3L;MFSD4B

REV3L;MFSD4B

CUI:	C0523465
Disease:

Serum albumin measurement

0.700

GeneticVariation

GWASDB

Genome-wide association study identifies multiple loci influencing human serum metabolite levels.

22286219

2012

dbSNP:

rs10485124

Entrez Id:	5980;91749
Gene Symbol:	REV3L;MFSD4B

REV3L;MFSD4B

CUI:	C0523465
Disease:

Serum albumin measurement

0.700

GeneticVariation

GWASDB

Genome-wide association study identifies multiple loci influencing human serum metabolite levels.

22286219

2012

dbSNP:

rs1061388

Entrez Id:	5980;91749
Gene Symbol:	REV3L;MFSD4B

REV3L;MFSD4B

CUI:	C0523465
Disease:

Serum albumin measurement

0.700

GeneticVariation

GWASDB

Genome-wide association study identifies multiple loci influencing human serum metabolite levels.

22286219

2012

dbSNP:

rs10872067

Entrez Id:	5980
Gene Symbol:	REV3L

REV3L

CUI:	C0523465
Disease:

Serum albumin measurement

0.700

GeneticVariation

GWASDB

Genome-wide association study identifies multiple loci influencing human serum metabolite levels.

22286219

2012

dbSNP:

rs110732

Entrez Id:	5980;91749
Gene Symbol:	REV3L;MFSD4B

REV3L;MFSD4B

CUI:	C0523465
Disease:

Serum albumin measurement

0.700

GeneticVariation

GWASDB

Genome-wide association study identifies multiple loci influencing human serum metabolite levels.

22286219

2012

dbSNP:

rs11153287

Entrez Id:	5980;91749
Gene Symbol:	REV3L;MFSD4B

REV3L;MFSD4B

CUI:	C0523465
Disease:

Serum albumin measurement

0.700

GeneticVariation

GWASDB

Genome-wide association study identifies multiple loci influencing human serum metabolite levels.

22286219

2012

dbSNP:

rs11153288

Entrez Id:	5980;91749
Gene Symbol:	REV3L;MFSD4B

REV3L;MFSD4B

CUI:	C0523465
Disease:

Serum albumin measurement

0.700

GeneticVariation

GWASDB

Genome-wide association study identifies multiple loci influencing human serum metabolite levels.

22286219

2012

dbSNP:

rs11153290

Entrez Id:	5980;91749
Gene Symbol:	REV3L;MFSD4B

REV3L;MFSD4B

CUI:	C0523465
Disease:

Serum albumin measurement

0.700

GeneticVariation

GWASDB

Genome-wide association study identifies multiple loci influencing human serum metabolite levels.

22286219

2012

dbSNP:

rs11153291

Entrez Id:	5980;91749
Gene Symbol:	REV3L;MFSD4B

REV3L;MFSD4B

CUI:	C0523465
Disease:

Serum albumin measurement

0.700

GeneticVariation

GWASDB

Genome-wide association study identifies multiple loci influencing human serum metabolite levels.

22286219

2012