RGS2, regulator of G protein signaling 2, 5997

N. diseases: 109; N. variants: 8
Disease: Phobia, Social ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4606
rs4606
Entrez Id: 5997
Gene Symbol: RGS2
RGS2
CUI: C0031572
Disease:
Phobia, Social 		0.010 GeneticVariation BEFREE In independent samples, RGS2 markers, including rs4606, which has previously been associated with RGS2 expression, were also associated with introversion (a core personality trait in social anxiety disorder) and with increased limbic activation (insular cortex and amygdala) during emotion processing (brain phenotypes correlated with social anxiety). 18316676 2008