RORC, RAR related orphan receptor C, 6097

N. diseases: 88; N. variants: 6
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4845604
rs4845604
Entrez Id: 6097
Gene Symbol: RORC
RORC
CUI: C0021390
Disease:
Inflammatory Bowel Diseases 		0.800 GeneticVariation GWASCAT Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. 28067908 2017
dbSNP: rs4845604
rs4845604
Entrez Id: 6097
Gene Symbol: RORC
RORC
CUI: C0021390
Disease:
Inflammatory Bowel Diseases 		G 0.800 GeneticVariation GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919 2015
dbSNP: rs774357869
rs774357869
Entrez Id: 6097
Gene Symbol: RORC
RORC
CUI: C4225266
Disease:
IMMUNODEFICIENCY 42 		0.800 GeneticVariation UNIPROT IMMUNODEFICIENCIES. Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations. 26160376 2015
dbSNP: rs4845604
rs4845604
Entrez Id: 6097
Gene Symbol: RORC
RORC
CUI: C0021390
Disease:
Inflammatory Bowel Diseases 		G 0.800 GeneticVariation GWASCAT Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. 23128233 2012
dbSNP: rs4845604
rs4845604
Entrez Id: 6097
Gene Symbol: RORC
RORC
CUI: C0021390
Disease:
Inflammatory Bowel Diseases 		G 0.800 GeneticVariation GWASDB Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. 23128233 2012
dbSNP: rs774357869
rs774357869
Entrez Id: 6097
Gene Symbol: RORC
RORC
CUI: C4225266
Disease:
IMMUNODEFICIENCY 42 		A 0.800 CausalMutation CLINVAR
dbSNP: rs3828058
rs3828058
Entrez Id: 6097
Gene Symbol: RORC
RORC
CUI: C0004096
Disease:
Asthma 		A 0.700 GeneticVariation GWASCAT Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis. 31619474 2019
dbSNP: rs4845604
rs4845604
Entrez Id: 6097
Gene Symbol: RORC
RORC
CUI: C0264408
Disease:
Childhood asthma 		0.700 GeneticVariation GWASCAT Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. 30929738 2019
dbSNP: rs4845604
rs4845604
Entrez Id: 6097
Gene Symbol: RORC
RORC
CUI: C0004096
Disease:
Asthma 		G 0.700 GeneticVariation GWASCAT Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. 30929738 2019
dbSNP: rs4845604
rs4845604
Entrez Id: 6097
Gene Symbol: RORC
RORC
CUI: C0035242
Disease:
Respiratory Tract Diseases 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs4845604
rs4845604
Entrez Id: 6097
Gene Symbol: RORC
RORC
CUI: C0013595
Disease:
Eczema 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs11204896
rs11204896
Entrez Id: 6097
Gene Symbol: RORC
RORC
CUI: C1527304
Disease:
Allergic Reaction 		C 0.700 GeneticVariation GWASCAT Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology. 29083406 2017
dbSNP: rs4845604
rs4845604
Entrez Id: 6097
Gene Symbol: RORC
RORC
CUI: C0009324
Disease:
Ulcerative Colitis 		0.700 GeneticVariation GWASCAT Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. 28067908 2017
dbSNP: rs4845604
rs4845604
Entrez Id: 6097
Gene Symbol: RORC
RORC
CUI: C0010346
Disease:
Crohn Disease 		0.700 GeneticVariation GWASCAT Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. 28067908 2017
dbSNP: rs4845604
rs4845604
Entrez Id: 6097
Gene Symbol: RORC
RORC
CUI: C0038013
Disease:
Ankylosing spondylitis 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
dbSNP: rs4845604
rs4845604
Entrez Id: 6097
Gene Symbol: RORC
RORC
CUI: C0010346
Disease:
Crohn Disease 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
dbSNP: rs4845604
rs4845604
Entrez Id: 6097
Gene Symbol: RORC
RORC
CUI: C0033860
Disease:
Psoriasis 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
dbSNP: rs4845604
rs4845604
Entrez Id: 6097
Gene Symbol: RORC
RORC
CUI: C0009324
Disease:
Ulcerative Colitis 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
dbSNP: rs4845604
rs4845604
Entrez Id: 6097
Gene Symbol: RORC
RORC
CUI: C0008313
Disease:
Cholangitis, Sclerosing 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
dbSNP: rs4845604
rs4845604
Entrez Id: 6097
Gene Symbol: RORC
RORC
CUI: C0009324
Disease:
Ulcerative Colitis 		G 0.700 GeneticVariation GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919 2015
dbSNP: rs4845604
rs4845604
Entrez Id: 6097
Gene Symbol: RORC
RORC
CUI: C0010346
Disease:
Crohn Disease 		G 0.700 GeneticVariation GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919 2015
dbSNP: rs863225091
rs863225091
Entrez Id: 6097
Gene Symbol: RORC
RORC
CUI: C4225266
Disease:
IMMUNODEFICIENCY 42 		A 0.700 CausalMutation CLINVAR
dbSNP: rs863225092
rs863225092
Entrez Id: 6097
Gene Symbol: RORC
RORC
CUI: C4225266
Disease:
IMMUNODEFICIENCY 42 		A 0.700 CausalMutation CLINVAR