RPS6KB1, ribosomal protein S6 kinase B1, 6198

N. diseases: 169; N. variants: 4
Disease: Multiple Sclerosis ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs180515
rs180515
Entrez Id: 6198
Gene Symbol: RPS6KB1
RPS6KB1
CUI: C0026769
Disease:
Multiple Sclerosis 		0.820 GeneticVariation BEFREE In the present study, we examined the association between two SNPs in RPS6KB1 (rs180515) and CD86 (rs9282641) with MS in Iranian population. 28079472 2017
dbSNP: rs180515
rs180515
Entrez Id: 6198
Gene Symbol: RPS6KB1
RPS6KB1
CUI: C0026769
Disease:
Multiple Sclerosis 		0.820 GeneticVariation BEFREE All five tested single nucleotide polymorphisms showed consistent and statistically significant evidence for association with multiple sclerosis in our validation data sets (rs228614: odds ratio = 0.91, P = 2.4 × 10(-6); rs630923: odds ratio = 0.89, P = 1.2 × 10(-4); rs2744148: odds ratio = 1.14, P = 1.8 × 10(-6); rs180515: odds ratio = 1.12, P = 5.2 × 10(-7); rs6062314: odds ratio = 0.90, P = 4.3 × 10(-3)). 23739915 2013
dbSNP: rs180515
rs180515
Entrez Id: 6198
Gene Symbol: RPS6KB1
RPS6KB1
CUI: C0026769
Disease:
Multiple Sclerosis 		G 0.820 GeneticVariation GWASCAT Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. 21833088 2011
dbSNP: rs180515
rs180515
Entrez Id: 6198
Gene Symbol: RPS6KB1
RPS6KB1
CUI: C0026769
Disease:
Multiple Sclerosis 		G 0.820 GeneticVariation GWASDB Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. 21833088 2011