BDNF, brain derived neurotrophic factor, 627

N. diseases: 992; N. variants: 56
Disease: Mental Depression ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs893924483
rs893924483
Entrez Id: 627;497258
Gene Symbol: BDNF;BDNF-AS
BDNF;BDNF-AS
CUI: C0011570
Disease:
Mental Depression 		0.020 GeneticVariation BEFREE To investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV. 23157339 2013
dbSNP: rs893924483
rs893924483
Entrez Id: 627;497258
Gene Symbol: BDNF;BDNF-AS
BDNF;BDNF-AS
CUI: C0011570
Disease:
Mental Depression 		0.020 GeneticVariation BEFREE Two common functional polymorphisms in catechol-O-methyltransferase (COMT Val158Met) and brain-derived neurotrophic factor (BDNF Val66Met) genes have been implicated in the neurobiology of anxiety and depression. 17941097 2008