BDNF, brain derived neurotrophic factor, 627

N. diseases: 992; N. variants: 56
Disease: Depressive disorder ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs7103411
rs7103411
Entrez Id: 627;497258
Gene Symbol: BDNF;BDNF-AS
BDNF;BDNF-AS
CUI: C0011581
Disease:
Depressive disorder 		0.030 GeneticVariation BEFREE Three single-nucleotide polymorphisms (rs6265, rs7103411 and rs908867) were also found to modify the association between depression and promoter I methylation. 26285129 2015
dbSNP: rs7103411
rs7103411
Entrez Id: 627;497258
Gene Symbol: BDNF;BDNF-AS
BDNF;BDNF-AS
CUI: C0011581
Disease:
Depressive disorder 		0.030 GeneticVariation BEFREE As a tool in psychopathology research, T-ARMS was shown to be capable of detecting five common SNPs in the BDNF gene (rs6265, rs988748, rs11030104, 11757G/C and rs7103411), which are all SNPs with previously demonstrated clinical relevance to schizophrenia and depression. 26118823 2015
dbSNP: rs7103411
rs7103411
Entrez Id: 627;497258
Gene Symbol: BDNF;BDNF-AS
BDNF;BDNF-AS
CUI: C0011581
Disease:
Depressive disorder 		0.030 GeneticVariation BEFREE However, BDNF rs7103411 and rs6265 similarly predicted worse treatment response over 6 wk in clinical subtypes of depression such as melancholic depression only (rs7103411: TT < CC, p = 0.003; rs6265: GG < AA, p = 0.001). 19236730 2010