SORT1, sortilin 1, 6272

N. diseases: 111; N. variants: 8
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1963869
rs1963869
Entrez Id: 6272
Gene Symbol: SORT1
SORT1
CUI: C0017654
Disease:
Glomerular Filtration Rate 		G 0.700 GeneticVariation GWASCAT Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis. 31015462 2019
dbSNP: rs10127790
rs10127790
Entrez Id: 6272
Gene Symbol: SORT1
SORT1
CUI: C0017654
Disease:
Glomerular Filtration Rate 		T 0.700 GeneticVariation GWASCAT 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function. 28452372 2017
dbSNP: rs10127790
rs10127790
Entrez Id: 6272
Gene Symbol: SORT1
SORT1
CUI: C0201976
Disease:
Creatinine measurement, serum (procedure) 		T 0.700 GeneticVariation GWASCAT 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function. 28452372 2017
dbSNP: rs11102974
rs11102974
Entrez Id: 6272
Gene Symbol: SORT1
SORT1
CUI: C0021704
Disease:
Intelligence 		0.700 GeneticVariation GWASCAT Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets. 29186694 2017
dbSNP: rs17646665
rs17646665
Entrez Id: 6272
Gene Symbol: SORT1
SORT1
CUI: C1445957
Disease:
Serum total cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs17646665
rs17646665
Entrez Id: 6272
Gene Symbol: SORT1
SORT1
CUI: C0202117
Disease:
Low density lipoprotein cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs17646665
rs17646665
Entrez Id: 6272
Gene Symbol: SORT1
SORT1
CUI: C0428474
Disease:
Serum LDL cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs17646731
rs17646731
Entrez Id: 6272
Gene Symbol: SORT1
SORT1
CUI: C0428474
Disease:
Serum LDL cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs17646731
rs17646731
Entrez Id: 6272
Gene Symbol: SORT1
SORT1
CUI: C1445957
Disease:
Serum total cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs17646731
rs17646731
Entrez Id: 6272
Gene Symbol: SORT1
SORT1
CUI: C0202117
Disease:
Low density lipoprotein cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs4970843
rs4970843
Entrez Id: 6272
Gene Symbol: SORT1
SORT1
CUI: C0428474
Disease:
Serum LDL cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs4970843
rs4970843
Entrez Id: 6272
Gene Symbol: SORT1
SORT1
CUI: C1445957
Disease:
Serum total cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs4970843
rs4970843
Entrez Id: 6272
Gene Symbol: SORT1
SORT1
CUI: C0202117
Disease:
Low density lipoprotein cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs17646665
rs17646665
Entrez Id: 6272
Gene Symbol: SORT1
SORT1
CUI: C0002395
Disease:
Alzheimer's Disease 		0.010 GeneticVariation BEFREE The SNP rs17646665, located in a non-coding region of the SORT1 gene, remained significantly associated with decreased risk of AD after multiple testing (pc = 0.0061). 27392867 2016
dbSNP: rs1880670
rs1880670
Entrez Id: 6272
Gene Symbol: SORT1
SORT1
CUI: C0002395
Disease:
Alzheimer's Disease 		0.010 GeneticVariation BEFREE Our meta-analysis suggested that rs1880670G/A, and rs2177369 G/A polymorphisms were not risk factors for AD. 27390868 2016
dbSNP: rs464218
rs464218
Entrez Id: 6272
Gene Symbol: SORT1
SORT1
CUI: C0948008
Disease:
Ischemic stroke 		0.010 GeneticVariation BEFREE No association was found between the SNPs of rs599839, rs464218 and rs6698843 at the CELSR2-PSRC1-SORT1 and the risk of CAD or IS. 26464717 2015
dbSNP: rs464218
rs464218
Entrez Id: 6272
Gene Symbol: SORT1
SORT1
CUI: C1956346
Disease:
Coronary Artery Disease 		0.010 GeneticVariation BEFREE No association was found between the SNPs of rs599839, rs464218 and rs6698843 at the CELSR2-PSRC1-SORT1 and the risk of CAD or IS. 26464717 2015