CCL2, C-C motif chemokine ligand 2, 6347

N. diseases: 1157; N. variants: 8
Disease: Non-Small Cell Lung Carcinoma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3760396
rs3760396
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0007131
Disease:
Non-Small Cell Lung Carcinoma 		0.020 GeneticVariation BEFREE Our study suggested rs3760396 polymorphism of CCL2 is associated not only with prognosis of NSCLC, but also with risk of lung cancer in a subtype-specific manner. 27145753 2016
dbSNP: rs3760396
rs3760396
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0007131
Disease:
Non-Small Cell Lung Carcinoma 		0.020 GeneticVariation BEFREE The results showed that variant genotypes of CCL2 rs3760396 and CCL8 rs3138035 were associated with a significantly decreased risk of death for NSCLC (dominant model: adjusted HR=0.65, 95% CI=0.48-0.89 for rs3760396; dominant model: adjusted HR=0.65, 95% CI=0.49-0.86 for rs3138035), while CXCL12 rs1804429 was associated with an increased risk of death for NSCLC (CC vs AA: adjusted HR=6.03, 95% CI=1.44-25.24). 21514686 2011