DisGeNET - a database of gene-disease associations

NOD2, nucleotide binding oligomerization domain containing 2, 64127

N. diseases: 9; N. variants: 8

Source: GWASCAT ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs2066844

Entrez Id:	64127
Gene Symbol:	NOD2

NOD2

CUI:	C0004096
Disease:

Asthma

0.700

GeneticVariation

GWASCAT

Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

30929738

2019

dbSNP:

rs2066844

Entrez Id:	64127
Gene Symbol:	NOD2

NOD2

CUI:	C0264408
Disease:

Childhood asthma

0.700

GeneticVariation

GWASCAT

Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.

31036433

2019

dbSNP:

rs2066844

Entrez Id:	64127
Gene Symbol:	NOD2

NOD2

CUI:	C0264408
Disease:

Childhood asthma

0.700

GeneticVariation

GWASCAT

Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

30929738

2019

dbSNP:

rs2066844

Entrez Id:	64127
Gene Symbol:	NOD2

NOD2

CUI:	C0149745
Disease:

Oral Ulcer

0.700

GeneticVariation

GWASCAT

Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci.

30837455

2019

dbSNP:

rs2066845

Entrez Id:	64127
Gene Symbol:	NOD2

NOD2

CUI:	C0008313
Disease:

Cholangitis, Sclerosing

0.700

GeneticVariation

GWASCAT

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

26974007

2016

dbSNP:

rs5743293

Entrez Id:	64127
Gene Symbol:	NOD2

NOD2

CUI:	C0008313
Disease:

Cholangitis, Sclerosing

0.700

GeneticVariation

GWASCAT

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

26974007

2016

dbSNP:

rs5743293

Entrez Id:	64127
Gene Symbol:	NOD2

NOD2

CUI:	C0009324
Disease:

Ulcerative Colitis

0.700

GeneticVariation

GWASCAT

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

26974007

2016

dbSNP:

rs5743293

Entrez Id:	64127
Gene Symbol:	NOD2

NOD2

CUI:	C0038013
Disease:

Ankylosing spondylitis

0.700

GeneticVariation

GWASCAT

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

26974007

2016

dbSNP:

rs5743293

Entrez Id:	64127
Gene Symbol:	NOD2

NOD2

CUI:	C0033860
Disease:

Psoriasis

0.700

GeneticVariation

GWASCAT

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

26974007

2016

dbSNP:

rs72796367

Entrez Id:	64127
Gene Symbol:	NOD2

NOD2

CUI:	C0010346
Disease:

Crohn Disease

0.700

GeneticVariation

GWASCAT

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

26974007

2016

dbSNP:

rs72796367

Entrez Id:	64127
Gene Symbol:	NOD2

NOD2

CUI:	C0008313
Disease:

Cholangitis, Sclerosing

0.700

GeneticVariation

GWASCAT

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

26974007

2016

dbSNP:

rs72796367

Entrez Id:	64127
Gene Symbol:	NOD2

NOD2

CUI:	C0033860
Disease:

Psoriasis

0.700

GeneticVariation

GWASCAT

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

26974007

2016

dbSNP:

rs72796367

Entrez Id:	64127
Gene Symbol:	NOD2

NOD2

CUI:	C0038013
Disease:

Ankylosing spondylitis

0.700

GeneticVariation

GWASCAT

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

26974007

2016

dbSNP:

rs72796367

Entrez Id:	64127
Gene Symbol:	NOD2

NOD2

CUI:	C0009324
Disease:

Ulcerative Colitis

0.700

GeneticVariation

GWASCAT

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

26974007

2016

dbSNP:

rs2066845

Entrez Id:	64127
Gene Symbol:	NOD2

NOD2

CUI:	C0033860
Disease:

Psoriasis

0.710

GeneticVariation

GWASCAT

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

26974007

2016

dbSNP:

rs2066845

Entrez Id:	64127
Gene Symbol:	NOD2

NOD2

CUI:	C0038013
Disease:

Ankylosing spondylitis

0.730

GeneticVariation

GWASCAT

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

26974007

2016

dbSNP:

rs2066844

Entrez Id:	64127
Gene Symbol:	NOD2

NOD2

CUI:	C0021390
Disease:

Inflammatory Bowel Diseases

0.790

GeneticVariation

GWASCAT

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.

28067908

2017

dbSNP:

rs2066845

Entrez Id:	64127
Gene Symbol:	NOD2

NOD2

CUI:	C0009324
Disease:

Ulcerative Colitis

0.800

GeneticVariation

GWASCAT

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

26974007

2016

dbSNP:

rs5743289

Entrez Id:	64127
Gene Symbol:	NOD2

NOD2

CUI:	C0021390
Disease:

Inflammatory Bowel Diseases

0.800

GeneticVariation

GWASCAT

Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease.

18758464

2008

dbSNP:

rs17221417

Entrez Id:	64127
Gene Symbol:	NOD2

NOD2

CUI:	C0010346
Disease:

Crohn Disease

0.810

GeneticVariation

GWASCAT

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.

17554300

2007

dbSNP:

rs5743289

Entrez Id:	64127
Gene Symbol:	NOD2

NOD2

CUI:	C0010346
Disease:

Crohn Disease

0.810

GeneticVariation

GWASCAT

Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4.

17447842

2007

dbSNP:

rs5743289

Entrez Id:	64127
Gene Symbol:	NOD2

NOD2

CUI:	C0010346
Disease:

Crohn Disease

0.810

GeneticVariation

GWASCAT

Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci.

17804789

2007

dbSNP:

rs2076756

Entrez Id:	64127
Gene Symbol:	NOD2

NOD2

CUI:	C0021390
Disease:

Inflammatory Bowel Diseases

0.820

GeneticVariation

GWASCAT

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.

17068223

2006

dbSNP:

rs5743293

Entrez Id:	64127
Gene Symbol:	NOD2

NOD2

CUI:	C0010346
Disease:

Crohn Disease

0.830

GeneticVariation

GWASCAT

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

26974007

2016

dbSNP:

rs2076756

Entrez Id:	64127
Gene Symbol:	NOD2

NOD2

CUI:	C0010346
Disease:

Crohn Disease

0.830

GeneticVariation

GWASCAT

A genome-wide association study on a southern European population identifies a new Crohn's disease susceptibility locus at RBX1-EP300.

22936669

2013