SHBG, sex hormone binding globulin, 6462

N. diseases: 368; N. variants: 20
Disease: Male infertility ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs6259
rs6259
Entrez Id: 6462
Gene Symbol: SHBG
SHBG
CUI: C0021364
Disease:
Male infertility 		0.020 GeneticVariation BEFREE Also, genotype frequencies, allele frequency, and haplotype were all analyzed in both groups.There were statistical differences in A allele frequency (P = .017) and GA genotype frequency (P = .016) of SHBG gene rs6259 locus and in CC genotype frequency of SHBG gene rs727428 locus (P = .034) between the 2 groups.Male infertility is associated with GA genotype and A allele of rs6259 locus, as well as CC genotype of rs727428 locus in SHBG gene. 28796064 2017
dbSNP: rs6259
rs6259
Entrez Id: 6462
Gene Symbol: SHBG
SHBG
CUI: C0021364
Disease:
Male infertility 		0.020 GeneticVariation BEFREE Association of the (TAAAA)n repeat and Asp327Asn polymorphisms in the sex hormone-binding globulin (SHBG) gene with idiopathic male infertility and relation to serum SHBG concentrations. 20974254 2011