Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2306363
rs2306363
Entrez Id: 6494
Gene Symbol: SIPA1
SIPA1
CUI: C1305849
Disease:
Diastolic blood pressure measurement
T 0.700 GeneticVariation GWASCAT Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. 29912962 2018
dbSNP: rs2306363
rs2306363
Entrez Id: 6494
Gene Symbol: SIPA1
SIPA1
CUI: C0428886
Disease:
Mean blood pressure
T 0.700 GeneticVariation GWASCAT Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. 29912962 2018
dbSNP: rs2306363
rs2306363
Entrez Id: 6494
Gene Symbol: SIPA1
SIPA1
CUI: C0871470
Disease:
Systolic Pressure
T 0.700 GeneticVariation GWASCAT Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. 29912962 2018
dbSNP: rs931127
rs931127
Entrez Id: 6494;399909
Gene Symbol: SIPA1;PCNX3
SIPA1;PCNX3
CUI: C0242379
Disease:
Malignant neoplasm of lung
0.010 GeneticVariation BEFREE Our data suggest that the SNP rs931127A > G in the promoter of Sipa1 was significantly associated with lung cancer risk and metastasis, which may be a biomarker to predict the risk and metastasis of lung cancer. 23661532 2013
dbSNP: rs931127
rs931127
Entrez Id: 6494;399909
Gene Symbol: SIPA1;PCNX3
SIPA1;PCNX3
CUI: C0684249
Disease:
Carcinoma of lung
0.010 GeneticVariation BEFREE Our data suggest that the SNP rs931127A > G in the promoter of Sipa1 was significantly associated with lung cancer risk and metastasis, which may be a biomarker to predict the risk and metastasis of lung cancer. 23661532 2013
dbSNP: rs931127
rs931127
Entrez Id: 6494;399909
Gene Symbol: SIPA1;PCNX3
SIPA1;PCNX3
CUI: C1306460
Disease:
Primary malignant neoplasm of lung
0.010 GeneticVariation BEFREE Our data suggest that the SNP rs931127A > G in the promoter of Sipa1 was significantly associated with lung cancer risk and metastasis, which may be a biomarker to predict the risk and metastasis of lung cancer. 23661532 2013
dbSNP: rs931127
rs931127
Entrez Id: 6494;399909
Gene Symbol: SIPA1;PCNX3
SIPA1;PCNX3
CUI: C0027627
Disease:
Neoplasm Metastasis
0.020 GeneticVariation BEFREE Our data suggest that the SNP rs931127A > G in the promoter of Sipa1 was significantly associated with lung cancer risk and metastasis, which may be a biomarker to predict the risk and metastasis of lung cancer. 23661532 2013
dbSNP: rs931127
rs931127
Entrez Id: 6494;399909
Gene Symbol: SIPA1;PCNX3
SIPA1;PCNX3
CUI: C0006142
Disease:
Malignant neoplasm of breast
0.030 GeneticVariation BEFREE Overall, we found no significant associations between genetic variants of SIPA1 SNPs and breast cancer risk (per allele odds ratios, 95% confidence intervals (CI): rs931127-0.99, 0.93-1.06; rs3741378-1.03, 0.94-1.13; and, rs74642-0.98, 0.92-1.04). 19089925 2009
dbSNP: rs931127
rs931127
Entrez Id: 6494;399909
Gene Symbol: SIPA1;PCNX3
SIPA1;PCNX3
CUI: C0678222
Disease:
Breast Carcinoma
0.030 GeneticVariation BEFREE Overall, we found no significant associations between genetic variants of SIPA1 SNPs and breast cancer risk (per allele odds ratios, 95% confidence intervals (CI): rs931127-0.99, 0.93-1.06; rs3741378-1.03, 0.94-1.13; and, rs74642-0.98, 0.92-1.04). 19089925 2009
dbSNP: rs3741378
rs3741378
Entrez Id: 6494
Gene Symbol: SIPA1
SIPA1
CUI: C0678222
Disease:
Breast Carcinoma
0.030 GeneticVariation BEFREE Overall, we found no significant associations between genetic variants of SIPA1 SNPs and breast cancer risk (per allele odds ratios, 95% confidence intervals (CI): rs931127-0.99, 0.93-1.06; rs3741378-1.03, 0.94-1.13; and, rs74642-0.98, 0.92-1.04). 19089925 2009
dbSNP: rs3741378
rs3741378
Entrez Id: 6494
Gene Symbol: SIPA1
SIPA1
CUI: C0006142
Disease:
Malignant neoplasm of breast
0.030 GeneticVariation BEFREE Overall, we found no significant associations between genetic variants of SIPA1 SNPs and breast cancer risk (per allele odds ratios, 95% confidence intervals (CI): rs931127-0.99, 0.93-1.06; rs3741378-1.03, 0.94-1.13; and, rs74642-0.98, 0.92-1.04). 19089925 2009
dbSNP: rs3741378
rs3741378
Entrez Id: 6494
Gene Symbol: SIPA1
SIPA1
CUI: C0678222
Disease:
Breast Carcinoma
0.030 GeneticVariation BEFREE Results indicated significance with SIPA1 SNP rs3741378; the CC genotype was more frequently observed in the breast cancer group compared to the disease-free control group, indicating the variant C allele was associated with increased breast cancer incidence. 19765277 2009
dbSNP: rs3741378
rs3741378
Entrez Id: 6494
Gene Symbol: SIPA1
SIPA1
CUI: C0006142
Disease:
Malignant neoplasm of breast
0.030 GeneticVariation BEFREE Results indicated significance with SIPA1 SNP rs3741378; the CC genotype was more frequently observed in the breast cancer group compared to the disease-free control group, indicating the variant C allele was associated with increased breast cancer incidence. 19765277 2009
dbSNP: rs931127
rs931127
Entrez Id: 6494;399909
Gene Symbol: SIPA1;PCNX3
SIPA1;PCNX3
CUI: C0006142
Disease:
Malignant neoplasm of breast
0.030 GeneticVariation BEFREE SIPA1 SNPs rs931127 (5' near gene), and rs746429 (synonymous (Ala (A) to Ala (A)), did not show significant associations with breast cancer incidence, yet were associated with lymph node metastasis in the previous study. 19765277 2009
dbSNP: rs931127
rs931127
Entrez Id: 6494;399909
Gene Symbol: SIPA1;PCNX3
SIPA1;PCNX3
CUI: C0678222
Disease:
Breast Carcinoma
0.030 GeneticVariation BEFREE SIPA1 SNPs rs931127 (5' near gene), and rs746429 (synonymous (Ala (A) to Ala (A)), did not show significant associations with breast cancer incidence, yet were associated with lymph node metastasis in the previous study. 19765277 2009
dbSNP: rs931127
rs931127
Entrez Id: 6494;399909
Gene Symbol: SIPA1;PCNX3
SIPA1;PCNX3
CUI: C0686619
Disease:
Secondary malignant neoplasm of lymph node
0.010 GeneticVariation BEFREE SIPA1 SNPs rs931127 (5' near gene), and rs746429 (synonymous (Ala (A) to Ala (A)), did not show significant associations with breast cancer incidence, yet were associated with lymph node metastasis in the previous study. 19765277 2009
dbSNP: rs746429
rs746429
Entrez Id: 6494
Gene Symbol: SIPA1
SIPA1
CUI: C0006142
Disease:
Malignant neoplasm of breast
0.030 GeneticVariation BEFREE SIPA1 SNPs rs931127 (5' near gene), and rs746429 (synonymous (Ala (A) to Ala (A)), did not show significant associations with breast cancer incidence, yet were associated with lymph node metastasis in the previous study. 19765277 2009
dbSNP: rs746429
rs746429
Entrez Id: 6494
Gene Symbol: SIPA1
SIPA1
CUI: C0678222
Disease:
Breast Carcinoma
0.030 GeneticVariation BEFREE SIPA1 SNPs rs931127 (5' near gene), and rs746429 (synonymous (Ala (A) to Ala (A)), did not show significant associations with breast cancer incidence, yet were associated with lymph node metastasis in the previous study. 19765277 2009
dbSNP: rs746429
rs746429
Entrez Id: 6494
Gene Symbol: SIPA1
SIPA1
CUI: C0686619
Disease:
Secondary malignant neoplasm of lymph node
0.010 GeneticVariation BEFREE SIPA1 SNPs rs931127 (5' near gene), and rs746429 (synonymous (Ala (A) to Ala (A)), did not show significant associations with breast cancer incidence, yet were associated with lymph node metastasis in the previous study. 19765277 2009
dbSNP: rs2448490
rs2448490
Entrez Id: 6494
Gene Symbol: SIPA1
SIPA1
CUI: C0032181
Disease:
Platelet Count measurement
A 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs3741378
rs3741378
Entrez Id: 6494
Gene Symbol: SIPA1
SIPA1
CUI: C0871470
Disease:
Systolic Pressure
T 0.700 GeneticVariation GWASCAT The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. 27618452 2016
dbSNP: rs3741378
rs3741378
Entrez Id: 6494
Gene Symbol: SIPA1
SIPA1
CUI: C0027651
Disease:
Neoplasms
0.020 GeneticVariation BEFREE The variant 2760G>A and the -313G>A allele were associated with lymph node involvement (P = 0.0062 and P = 0.0083, respectively), and the variant 545C>T was associated with estrogen receptor negative tumors (P = 0.0012) and with progesterone negative tumors (P = 0.0339). 16563182 2006
dbSNP: rs746429
rs746429
Entrez Id: 6494
Gene Symbol: SIPA1
SIPA1
CUI: C0027651
Disease:
Neoplasms
0.030 GeneticVariation BEFREE The variant 2760G>A and the -313G>A allele were associated with lymph node involvement (P = 0.0062 and P = 0.0083, respectively), and the variant 545C>T was associated with estrogen receptor negative tumors (P = 0.0012) and with progesterone negative tumors (P = 0.0339). 16563182 2006
dbSNP: rs746429
rs746429
Entrez Id: 6494
Gene Symbol: SIPA1
SIPA1
CUI: C0006142
Disease:
Malignant neoplasm of breast
0.030 GeneticVariation BEFREE This meta-analysis suggests that rs746429 is associated with the risk of breas</span>t cancer. 24006220 2014
dbSNP: rs746429
rs746429
Entrez Id: 6494
Gene Symbol: SIPA1
SIPA1
CUI: C0678222
Disease:
Breast Carcinoma
0.030 GeneticVariation BEFREE This meta-analysis suggests that rs746429 is associated with the risk of breas</span>t cancer. 24006220 2014