Disease: Neoplasms ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs746429
rs746429
Entrez Id: 6494
Gene Symbol: SIPA1
SIPA1
CUI: C0027651
Disease:
Neoplasms 		0.030 GeneticVariation BEFREE Two SIPA1 SNPs, rs746429 and rs2306364, were associated with decreased risk of triple-negative tumors (P trend = 0.04 and 0.07, respectively). 23771732 2013
dbSNP: rs746429
rs746429
Entrez Id: 6494
Gene Symbol: SIPA1
SIPA1
CUI: C0027651
Disease:
Neoplasms 		0.030 GeneticVariation BEFREE To test this hypothesis, we genotyped 3 single nucleotide polymorphisms (SNP) located at -3092 (A<G, rs931127), exon 3-135 (C>T, rs3741378), and exon 14 + 14 (C>T, rs746429), and examined them in relation to breast cancer risk and overall survival, stratified by tumor characteristics in 2 independent case-control studies conducted in Poland (1,995 cases, 2,296 controls) and in Britain (2,142 cases, 2,257 controls). 19089925 2009
dbSNP: rs746429
rs746429
Entrez Id: 6494
Gene Symbol: SIPA1
SIPA1
CUI: C0027651
Disease:
Neoplasms 		0.030 GeneticVariation BEFREE The variant 2760G>A and the -313G>A allele were associated with lymph node involvement (P = 0.0062 and P = 0.0083, respectively), and the variant 545C>T was associated with estrogen receptor negative tumors (P = 0.0012) and with progesterone negative tumors (P = 0.0339). 16563182 2006