SKIV2L, Ski2 like RNA helicase, 6499

N. diseases: 96; N. variants: 24
Disease: Age related macular degeneration ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs453821
rs453821
Entrez Id: 1589;6499
Gene Symbol: CYP21A2;SKIV2L
CYP21A2;SKIV2L
CUI: C0242383
Disease:
Age related macular degeneration 		0.010 GeneticVariation BEFREE The SKIV2L SNPs rs429608 and rs453821 were significantly associated with neovascular AMD (P = 7.39 × 10(-5); odds ratio [OR], 0.22; 95% confidence interval [CI], 0.10-0.50; and P = 0.001; OR, 0.38; 95% CI, 0.21-0.70, respectively), whereas borderline associations were detected for C2 rs547154 (P = 0.002) and RDBP rs760070 (P = 0.003). 23260260 2013