<b>Conclusion:</b> The results of the present study did not indicate an association of polymorphism-181 A/C (rs4354668) in <i>SLC1A2</i> and rs2486001 in <i>SLC6A9</i> with onset of schizophrenia and its psychopathology in a Polish population.
We examined rs4354668 in 88 clinically stabilized patients with schizophrenia, treated with CRT and assessed at enrolment, at the end of CRT and after 3 months.
The rs4354668 SNP was identified to be significantly associated with SCZ in both datasets, and a similar pattern was also observed in the two-stage study on conducting imputation and haplotype association analyses.
To evaluate the effect of functional polymorphisms (rs4354668 and rs2731880) of the excitatory amino acid transporters (EAAT1 and 2) on the cognitive dysfunction that characterizes schizophrenia.