SLC6A2, solute carrier family 6 member 2, 6530

N. diseases: 238; N. variants: 24
Disease: Depressive disorder ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs5569
rs5569
Entrez Id: 6530
Gene Symbol: SLC6A2
SLC6A2
CUI: C0011581
Disease:
Depressive disorder 		0.010 GeneticVariation BEFREE In self-identified white patients with major depressive disorder (N=126) treated with open-label duloxetine (60-120 mg/d), a significant association of (P=0.020) of a composite risk score (based on SLC6A2 rs5569 [G1287A] AA, HTR1A rs6295 [C(-1019)G] GG, and COMT rs174697 AA/AG) with 17-item Hamilton Depression Rating Scale total score change from baseline to 12 weeks was observed. 22727709 2012