SMO, smoothened, frizzled class receptor, 6608

N. diseases: 215; N. variants: 13
Disease: Carcinoma, Basal Cell ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs17710891
rs17710891
Entrez Id: 6608
Gene Symbol: SMO
SMO
CUI: C4721806
Disease:
Carcinoma, Basal Cell 		C 0.700 CausalMutation CLINVAR Smoothened variants explain the majority of drug resistance in basal cell carcinoma. 25759020 2015
dbSNP: rs17710891
rs17710891
Entrez Id: 6608
Gene Symbol: SMO
SMO
CUI: C4721806
Disease:
Carcinoma, Basal Cell 		C 0.700 CausalMutation CLINVAR Vismodegib. 22679179 2012
dbSNP: rs17710891
rs17710891
Entrez Id: 6608
Gene Symbol: SMO
SMO
CUI: C4721806
Disease:
Carcinoma, Basal Cell 		C 0.700 CausalMutation CLINVAR Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma. 19726788 2009