SNCA, synuclein alpha, 6622

N. diseases: 449; N. variants: 66
Disease: Progressive cGVHD ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs104893877
rs104893877
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
CUI: C3539781
Disease:
Progressive cGVHD 		0.010 GeneticVariation BEFREE The two A53T heterozygotes had markedly different neuropathology and different parkin genotypes: A N167 homozygote had early onset rapidly progressive disease, early dementia, myoclonus and sleep disorder, while a S167 homozygote had late onset, slowly progressive disease and late dementia. 18389263 2008