SOD2, superoxide dismutase 2, 6648

N. diseases: 668; N. variants: 32
Disease: Liver carcinoma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs5746098
rs5746098
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
CUI: C2239176
Disease:
Liver carcinoma 		0.010 GeneticVariation BEFREE For the ECSOD Ala40Thr polymorphism, a significant association was observed between this polymorphism and HCC risk in non-hepatitis B virus (HBV) carriers but not in HBV carriers, and individuals with one 40Thr allele (Ala/Thr genotype) (OR = 2.13, 95 % CI = 1.25-3.64, P = 0.006) or at least one 40Thr allele (Ala/Thr and Thr/Thr genotype) (OR = 1.90, 95 % CI = 1.15-3.15, P = 0.012) showed significantly higher risk to HCC, compared with Ala/Ala genotype. 25894370 2015