SPP1, secreted phosphoprotein 1, 6696

N. diseases: 824; N. variants: 13
Disease: Lupus Erythematosus, Systemic ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1370031102
rs1370031102
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.020 GeneticVariation BEFREE While no association was found between SLE and the OPN 707 T/C and 1083 G/A polymorphisms, a significant association was identified between the OPN 1239 C allele and SLE (OR = 1.192, 95% CI = 1.008-1.410, p = 0.040), and between the OPN 9250 C allele and SLE in Asians (OR = 2.070, 95% CI = 1.570-2.730, p = 2.5 × 10<sup>-7</sup>). 27307447 2017
dbSNP: rs1370031102
rs1370031102
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.020 GeneticVariation BEFREE A silent polymorphism (707C>T, rs1126616) of osteopontin was significantly associated with SLE. 11933203 2002