|
rs169068
|
SSTR5;SSTR5-AS1
|
Bipolar Disorder
|
|
0.010 |
GeneticVariation |
BEFREE |
For the British population we found association to B</span>PAD with missense mutation Leu48Met (P = 0.003) and missense mutation Pro335Leu (P = 0.004).
|
12192619 |
2002 |
|
rs169068
|
SSTR5;SSTR5-AS1
|
MAJOR AFFECTIVE DISORDER 4
|
|
0.010 |
GeneticVariation |
BEFREE |
For the British population we found association to B</span>PAD with missense mutation Leu48Met (P = 0.003) and missense mutation Pro335Leu (P = 0.004).
|
12192619 |
2002 |
|
rs169068
|
SSTR5;SSTR5-AS1
|
MAJOR AFFECTIVE DISORDER 6
|
|
0.010 |
GeneticVariation |
BEFREE |
For the British population we found association to B</span>PAD with missense mutation Leu48Met (P = 0.003) and missense mutation Pro335Leu (P = 0.004).
|
12192619 |
2002 |
|
rs169068
|
SSTR5;SSTR5-AS1
|
MAJOR AFFECTIVE DISORDER 2
|
|
0.010 |
GeneticVariation |
BEFREE |
For the British population we found association to B</span>PAD with missense mutation Leu48Met (P = 0.003) and missense mutation Pro335Leu (P = 0.004).
|
12192619 |
2002 |
|
rs169068
|
SSTR5;SSTR5-AS1
|
MAJOR AFFECTIVE DISORDER 1
|
|
0.010 |
GeneticVariation |
BEFREE |
For the British population we found association to B</span>PAD with missense mutation Leu48Met (P = 0.003) and missense mutation Pro335Leu (P = 0.004).
|
12192619 |
2002 |
|
rs34608001
|
SSTR5;SSTR5-AS1
|
MAJOR AFFECTIVE DISORDER 1
|
|
0.010 |
GeneticVariation |
BEFREE |
For the Danish population, association was suggested between silent SNP G573A and BPAD (P = 0.008).
|
12192619 |
2002 |
|
rs34608001
|
SSTR5;SSTR5-AS1
|
MAJOR AFFECTIVE DISORDER 2
|
|
0.010 |
GeneticVariation |
BEFREE |
For the Danish population, association was suggested between silent SNP G573A and BPAD (P = 0.008).
|
12192619 |
2002 |
|
rs34608001
|
SSTR5;SSTR5-AS1
|
Bipolar Disorder
|
|
0.010 |
GeneticVariation |
BEFREE |
For the Danish population, association was suggested between silent SNP G573A and BPAD (P = 0.008).
|
12192619 |
2002 |
|
rs34608001
|
SSTR5;SSTR5-AS1
|
MAJOR AFFECTIVE DISORDER 4
|
|
0.010 |
GeneticVariation |
BEFREE |
For the Danish population, association was suggested between silent SNP G573A and BPAD (P = 0.008).
|
12192619 |
2002 |
|
rs34608001
|
SSTR5;SSTR5-AS1
|
MAJOR AFFECTIVE DISORDER 6
|
|
0.010 |
GeneticVariation |
BEFREE |
For the Danish population, association was suggested between silent SNP G573A and BPAD (P = 0.008).
|
12192619 |
2002 |
|
rs4988483
|
SSTR5;SSTR5-AS1
|
Bipolar Disorder
|
|
0.010 |
GeneticVariation |
BEFREE |
For the British population we found association to BPAD with missense mutation Leu48Met</span> (P = 0.003) and missense mutation Pro335Leu (P = 0.004).
|
12192619 |
2002 |
|
rs4988483
|
SSTR5;SSTR5-AS1
|
MAJOR AFFECTIVE DISORDER 1
|
|
0.010 |
GeneticVariation |
BEFREE |
For the British population we found association to BPAD with missense mutation Leu48Met</span> (P = 0.003) and missense mutation Pro335Leu (P = 0.004).
|
12192619 |
2002 |
|
rs4988483
|
SSTR5;SSTR5-AS1
|
MAJOR AFFECTIVE DISORDER 6
|
|
0.010 |
GeneticVariation |
BEFREE |
For the British population we found association to BPAD with missense mutation Leu48Met</span> (P = 0.003) and missense mutation Pro335Leu (P = 0.004).
|
12192619 |
2002 |
|
rs4988483
|
SSTR5;SSTR5-AS1
|
MAJOR AFFECTIVE DISORDER 4
|
|
0.010 |
GeneticVariation |
BEFREE |
For the British population we found association to BPAD with missense mutation Leu48Met</span> (P = 0.003) and missense mutation Pro335Leu (P = 0.004).
|
12192619 |
2002 |
|
rs4988483
|
SSTR5;SSTR5-AS1
|
MAJOR AFFECTIVE DISORDER 2
|
|
0.010 |
GeneticVariation |
BEFREE |
For the British population we found association to BPAD with missense mutation Leu48Met</span> (P = 0.003) and missense mutation Pro335Leu (P = 0.004).
|
12192619 |
2002 |
|
rs4988483
|
SSTR5;SSTR5-AS1
|
Prostate carcinoma
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results suggest that genetic variation in the SSTR5 gene and, particularly, the rs4988483 single nucleotide polymorphism influence circulating IGFI and IGFBP3 hormone levels with no measurable effect on prostate cancer risk.
|
19423539 |
2009 |
|
rs4988483
|
SSTR5;SSTR5-AS1
|
Malignant neoplasm of prostate
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results suggest that genetic variation in the SSTR5 gene and, particularly, the rs4988483 single nucleotide polymorphism influence circulating IGFI and IGFBP3 hormone levels with no measurable effect on prostate cancer risk.
|
19423539 |
2009 |
|
rs169068
|
SSTR5;SSTR5-AS1
|
Malignant neoplasm of pancreas
|
|
0.010 |
GeneticVariation |
BEFREE |
These data suggest that SSTR5 P335L is a hypofunctional protein with a potentially harmful effect on function, as well as potential latent effect, and therefore it could affect the clinical response to somatostatin analog therapy for patients with pancreatic cancer.
|
21249361 |
2011 |
|
rs169068
|
SSTR5;SSTR5-AS1
|
Pancreatic carcinoma
|
|
0.010 |
GeneticVariation |
BEFREE |
These data suggest that SSTR5 P335L is a hypofunctional protein with a potentially harmful effect on function, as well as potential latent effect, and therefore it could affect the clinical response to somatostatin analog therapy for patients with pancreatic cancer.
|
21249361 |
2011 |
|
rs169068
|
SSTR5;SSTR5-AS1
|
Pancreatic Neoplasm
|
|
0.010 |
GeneticVariation |
BEFREE |
No somatic mutations were identified, but 3 nonsynonymous SSTR5 SNPs (P109S, L48M, and P335L) in pancreatic tumors were identified.
|
21692047 |
2011 |
|
rs4988483
|
SSTR5;SSTR5-AS1
|
Pancreatic Neoplasm
|
|
0.010 |
GeneticVariation |
BEFREE |
No somatic mutations were identified, but 3 nonsynonymous SSTR5 SNPs (P109S, L48M, and P335L) in pancreatic tumors were identified.
|
21692047 |
2011 |
|
rs4988483
|
SSTR5;SSTR5-AS1
|
Pancreatic carcinoma
|
|
0.010 |
GeneticVariation |
BEFREE |
Furthermore, the SSTR5 L48M AC variant and smoking had a joint effect on pancreatic cancer risk (p(interaction) = 0.035).
|
21692047 |
2011 |
|
rs4988483
|
SSTR5;SSTR5-AS1
|
Malignant neoplasm of pancreas
|
|
0.010 |
GeneticVariation |
BEFREE |
Furthermore, the SSTR5 L48M AC variant and smoking had a joint effect on pancreatic cancer risk (p(interaction) = 0.035).
|
21692047 |
2011 |
|
rs4988487
|
SSTR5;SSTR5-AS1
|
Pancreatic carcinoma
|
|
0.010 |
GeneticVariation |
BEFREE |
The SSTR5 P109S variant allele was associated with a 1.62-fold increased risk of pancreatic cancer (95% confidence interval [CI]: 1.08-2.43, P = 0.019).
|
21692047 |
2011 |
|
rs4988487
|
SSTR5;SSTR5-AS1
|
Malignant neoplasm of pancreas
|
|
0.010 |
GeneticVariation |
BEFREE |
The SSTR5 P109S variant allele was associated with a 1.62-fold increased risk of pancreatic cancer (95% confidence interval [CI]: 1.08-2.43, P = 0.019).
|
21692047 |
2011 |