rs10168266
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Sjogren's Syndrome
T
0.800
GeneticVariation
GWASDB
A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23.
24097066
2013
rs10168266
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Sjogren's Syndrome
T
0.800
GeneticVariation
GWASCAT
A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23.
24097066
2013
rs10168266
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Primary biliary cirrhosis
0.710
GeneticVariation
BEFREE
We detected significant associations with PBC susceptibility for several STAT4 SNPs (rs10168266 ; P = 9.4 × 10(-3), rs11889341; P = 1.2 × 10(-3), rs7574865; P = 4.0 × 10(-4), rs8179673; P = 2.0 × 10(-4), and rs10181656; P = 4.2 × 10(-5)).
24648611
2014
rs10168266
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Primary biliary cirrhosis
A
0.710
GeneticVariation
GWASCAT
A genome-wide association study identifies six novel risk loci for primary biliary cholangitis.
28425483
2017
rs10168266
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Rheumatoid Arthritis
0.700
GeneticVariation
GWASDB
Functional variants in NFKBIE and RTKN2 involved in activation of the NF-κB pathway are associated with rheumatoid arthritis in Japanese.
23028356
2012
rs10168266
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Rheumatoid Arthritis
0.700
GeneticVariation
GWASDB
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.
23143596
2012
rs10168266
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Lupus Erythematosus, Systemic
0.700
GeneticVariation
GWASDB
Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.
23273568
2013
rs10168266
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Neuromyelitis Optica
0.010
GeneticVariation
BEFREE
After correcting for multiple test comparisons, the minor alleles of four STAT4 SNPs exhibited significant association with increased risk of NMOSD (rs7574865 T, odds ratio [OR] = 1.66, 95% confidence interval [CI] 1.32-2.08, P <sub>corr</sub> = 0.000; rs10181656 G, OR = 1.62, 95% CI 1.29-2.03, P <sub>corr</sub> = 0.000; rs10168266 T, OR = 1.59, 95% CI 1.27-2.00, P <sub>corr</sub> = 0.001; and rs13426947 A, OR = 1.51, 95% CI 1.21-1.90, P <sub>corr</sub> = 0.004).
28852993
2017
rs10168266
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Systemic Scleroderma
0.010
GeneticVariation
BEFREE
The T-allele carriers of rs7574865 and rs10168266 were strongly associated with the presence of anti-topoisomerase I (ATA) and pulmonary fibrosis in SSc patients, as well as with diffuse cutaneous SSc (dcSSc).
23755762
2013
rs10168266
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Pulmonary Fibrosis
0.010
GeneticVariation
BEFREE
The T-allele carriers of rs7574865 and rs10168266 were strongly associated with the presence of anti-topoisomerase I (ATA) and pulmonary fibrosis in SSc patients, as well as with diffuse cutaneous SSc (dcSSc).
23755762
2013
rs10168266
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Hepatitis B
0.010
GeneticVariation
BEFREE
Further, haplotype-based association analysis indicated that the haplotype CTCTT, formed by SNPs rs8179673, rs7574865, rs4274624, rs11889341, and rs10168266 , was significantly associated with HBV infection (OR 0.87; 95 % CI 0.76, 0.99; P = 0.022) and clearance (OR 0.86; 95 % CI 0.75, 0.99; P = 0.018).
27444301
2016
rs10174238
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Oligoarticular Juvenile Idiopathic Arthritis
G
0.800
GeneticVariation
GWASCAT
Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.
23603761
2013
rs10174238
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Oligoarticular Juvenile Idiopathic Arthritis
0.800
GeneticVariation
GWASDB
Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.
23603761
2013
rs10174238
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Rheumatoid Arthritis, Systemic Juvenile
G
0.700
GeneticVariation
GWASCAT
Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.
23603761
2013
rs10174238
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Polyarticular Juvenile Idiopathic Arthritis, Rheumatoid Factor Negative
G
0.700
GeneticVariation
GWASCAT
Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.
23603761
2013
rs10174238
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Scleroderma, Limited
0.700
GeneticVariation
GWASCAT
Gene-level association analysis of systemic sclerosis: A comparison of African-Americans and White populations.
29293537
2018
rs10174238
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Systemic onset juvenile chronic arthritis
G
0.700
GeneticVariation
GWASCAT
Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.
23603761
2013
rs10174238
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Rheumatoid Arthritis
0.700
GeneticVariation
GWASCAT
Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases.
30573655
2019
rs10174238
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Lupus Erythematosus, Systemic
0.700
GeneticVariation
GWASCAT
Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases.
30573655
2019
rs10174238
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Juvenile-Onset Still Disease
G
0.700
GeneticVariation
GWASCAT
Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.
23603761
2013
rs10174238
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Juvenile pauciarticular chronic arthritis
G
0.700
GeneticVariation
GWASCAT
Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.
23603761
2013
rs10174238
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Systemic Scleroderma
0.700
GeneticVariation
GWASCAT
Gene-level association analysis of systemic sclerosis: A comparison of African-Americans and White populations.
29293537
2018
rs10174238
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Eosinophil count procedure
0.700
GeneticVariation
GWASCAT
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
30595370
2019
rs10174238
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Myositis
0.700
GeneticVariation
GWASCAT
Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases.
30573655
2019
rs10174238
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Systemic Scleroderma
0.700
GeneticVariation
GWASCAT
Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases.
30573655
2019