STK11, serine/threonine kinase 11, 6794

N. diseases: 372; N. variants: 145
Disease: Neoplastic Syndromes, Hereditary ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs376280361
rs376280361
Entrez Id: 6794
Gene Symbol: STK11
STK11
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		C 0.700 CausalMutation CLINVAR Structure of the LKB1-STRAD-MO25 complex reveals an allosteric mechanism of kinase activation. 19892943 2009
dbSNP: rs376280361
rs376280361
Entrez Id: 6794
Gene Symbol: STK11
STK11
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		C 0.700 CausalMutation CLINVAR High proportion of large genomic STK11 deletions in Peutz-Jeghers syndrome. 16287113 2005
dbSNP: rs376280361
rs376280361
Entrez Id: 6794
Gene Symbol: STK11
STK11
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		C 0.700 CausalMutation CLINVAR Functional analysis of LKB1/STK11 mutants and two aberrant isoforms found in Peutz-Jeghers Syndrome patients. 12552571 2003
dbSNP: rs376280361
rs376280361
Entrez Id: 6794
Gene Symbol: STK11
STK11
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		C 0.700 CausalMutation CLINVAR STK11 mutations in Peutz-Jeghers syndrome and sporadic colon cancer. 9809980 1998