rs59336
×
Entrez Id:
6926
Gene Symbol:
TBX3
TBX3
Adenocarcinoma of large intestine
T
0.700
GeneticVariation
GWASCAT
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.
23266556
2013
rs8853
×
Entrez Id:
6926
Gene Symbol:
TBX3
TBX3
Benign Prostatic Hyperplasia
C
0.700
GeneticVariation
GWASCAT
Genome-wide associations for benign prostatic hyperplasia reveal a genetic correlation with serum levels of PSA.
30410027
2018
rs1061651
×
Entrez Id:
6926
Gene Symbol:
TBX3
TBX3
Body Height
0.700
GeneticVariation
GWASCAT
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
30595370
2019
rs1061651
×
Entrez Id:
6926
Gene Symbol:
TBX3
TBX3
Breast Carcinoma
0.010
GeneticVariation
BEFREE
RUNX1_rs8130963 (odds ratio (OR) = 2.25; 95 % CI 1.42-3.56; P = 0.0005; dominant model), TBX3_rs8853 (OR = 2.04; 95 % CI 1.38-3.01; P = 0.0003; dominant model), TBX3_rs1061651 (OR= 2.14; 95 % CI1.43-3.18; P = 0.0002; dominant model), TTN_rs12465459 (OR = 2.02; 95 % confidence interval 1.33-3.07; P = 0.0009; dominant model), were the most significantly associated SNPs with BC risk.
26920143
2016
rs2242442
TBX3;LOC105370000
Breast Carcinoma
0.010
GeneticVariation
BEFREE
TBX3 was associated with BC risk (rs2242442 : OR = 0.76, 95% CI 0.64-0.92, dominant model) and with less aggressive tumour characteristics.
28238063
2017
rs8853
×
Entrez Id:
6926
Gene Symbol:
TBX3
TBX3
Breast Carcinoma
0.010
GeneticVariation
BEFREE
RUNX1_rs8130963 (odds ratio (OR) = 2.25; 95 % CI 1.42-3.56; P = 0.0005; dominant model), TBX3_rs8853 (OR = 2.04; 95 % CI 1.38-3.01; P = 0.0003; dominant model), TBX3_rs1061651 (OR= 2.14; 95 % CI1.43-3.18; P = 0.0002; dominant model), TTN_rs12465459 (OR = 2.02; 95 % confidence interval 1.33-3.07; P = 0.0009; dominant model), were the most significantly associated SNPs with BC risk.
26920143
2016
rs59336
×
Entrez Id:
6926
Gene Symbol:
TBX3
TBX3
Carcinoma of larynx
0.010
GeneticVariation
BEFREE
Univariate cox regression analysis indicated that four SNPs were associated (p < 0.05) with LC OS in the codominant genetic model compared to patients with the homozygous wild-type genotype: rs10088262 G/A (HR = 1.57), rs1665650 A/G (HR = 0.65); rs3802842 C/C (HR = 2.18), and rs59336 T/A and T/T (HR = 0.61 and 2.61, respectively).
28052013
2017
rs59336
×
Entrez Id:
6926
Gene Symbol:
TBX3
TBX3
COLORECTAL CANCER, SUSCEPTIBILITY TO, 1
T
0.700
GeneticVariation
GWASCAT
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.
23266556
2013
rs59336
×
Entrez Id:
6926
Gene Symbol:
TBX3
TBX3
COLORECTAL CANCER, SUSCEPTIBILITY TO, 10
T
0.700
GeneticVariation
GWASCAT
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.
23266556
2013
rs59336
×
Entrez Id:
6926
Gene Symbol:
TBX3
TBX3
COLORECTAL CANCER, SUSCEPTIBILITY TO, 12
T
0.700
GeneticVariation
GWASCAT
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.
23266556
2013
rs59336
×
Entrez Id:
6926
Gene Symbol:
TBX3
TBX3
COLORECTAL CANCER, SUSCEPTIBILITY TO, 3
T
0.700
GeneticVariation
GWASCAT
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.
23266556
2013
rs59336
×
Entrez Id:
6926
Gene Symbol:
TBX3
TBX3
Colorectal Carcinoma
T
0.810
GeneticVariation
GWASCAT
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.
23266556
2013
rs59336
×
Entrez Id:
6926
Gene Symbol:
TBX3
TBX3
Colorectal Carcinoma
T
0.810
GeneticVariation
GWASDB
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.
23266556
2013
rs59336
×
Entrez Id:
6926
Gene Symbol:
TBX3
TBX3
Colorectal Carcinoma
0.810
GeneticVariation
BEFREE
Of the three additional loci for which evidence of an association in Europeans has been previously described we failed to show an association between rs59336 (12q24.21) and CRC risk.
24737748
2014
rs515746
TBX3;LOC105370000
Colorectal Carcinoma
0.700
GeneticVariation
GWASDB
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.
23266556
2013
rs551510
×
Entrez Id:
6926
Gene Symbol:
TBX3
TBX3
Colorectal Carcinoma
0.700
GeneticVariation
GWASDB
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.
23266556
2013
rs59336
×
Entrez Id:
6926
Gene Symbol:
TBX3
TBX3
Colorectal Neoplasms
T
0.700
GeneticVariation
GWASCAT
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.
23266556
2013
rs201325654
×
Entrez Id:
6926
Gene Symbol:
TBX3
TBX3
Conotruncal defect
0.010
GeneticVariation
BEFREE
Our results indicate that the R608W and R616Q variants of TBX2 as well as the A192T and A562V variants of TBX3 contribute to CTD etiology; this was the first association of variants of TBX2 and TBX3 to CTD s based on a large population.
30223900
2018
rs768160499
TBX3;LOC105370000
Conotruncal defect
0.010
GeneticVariation
BEFREE
Our results indicate that the R608W and R616Q variants of TBX2 as well as the A192T and A562V variants of TBX3 contribute to CTD etiology; this was the first association of variants of TBX2 and TBX3 to CTD s based on a large population.
30223900
2018
rs8853
×
Entrez Id:
6926
Gene Symbol:
TBX3
TBX3
Lower Urinary Tract Symptoms
C
0.700
GeneticVariation
GWASCAT
Genome-wide associations for benign prostatic hyperplasia reveal a genetic correlation with serum levels of PSA.
30410027
2018
rs1061651
×
Entrez Id:
6926
Gene Symbol:
TBX3
TBX3
Malignant neoplasm of breast
0.010
GeneticVariation
BEFREE
RUNX1_rs8130963 (odds ratio (OR) = 2.25; 95 % CI 1.42-3.56; P = 0.0005; dominant model), TBX3_rs8853 (OR = 2.04; 95 % CI 1.38-3.01; P = 0.0003; dominant model), TBX3_rs1061651 (OR= 2.14; 95 % CI1.43-3.18; P = 0.0002; dominant model), TTN_rs12465459 (OR = 2.02; 95 % confidence interval 1.33-3.07; P = 0.0009; dominant model), were the most significantly associated SNPs with BC risk.
26920143
2016
rs2242442
TBX3;LOC105370000
Malignant neoplasm of breast
0.010
GeneticVariation
BEFREE
TBX3 was associated with BC risk (rs2242442 : OR = 0.76, 95% CI 0.64-0.92, dominant model) and with less aggressive tumour characteristics.
28238063
2017
rs8853
×
Entrez Id:
6926
Gene Symbol:
TBX3
TBX3
Malignant neoplasm of breast
0.010
GeneticVariation
BEFREE
RUNX1_rs8130963 (odds ratio (OR) = 2.25; 95 % CI 1.42-3.56; P = 0.0005; dominant model), TBX3_rs8853 (OR = 2.04; 95 % CI 1.38-3.01; P = 0.0003; dominant model), TBX3_rs1061651 (OR= 2.14; 95 % CI1.43-3.18; P = 0.0002; dominant model), TTN_rs12465459 (OR = 2.02; 95 % confidence interval 1.33-3.07; P = 0.0009; dominant model), were the most significantly associated SNPs with BC risk.
26920143
2016
rs59336
×
Entrez Id:
6926
Gene Symbol:
TBX3
TBX3
Malignant neoplasm of large intestine
T
0.700
GeneticVariation
GWASCAT
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.
23266556
2013
rs59336
×
Entrez Id:
6926
Gene Symbol:
TBX3
TBX3
Malignant tumor of colon
T
0.700
GeneticVariation
GWASCAT
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.
23266556
2013