HNF1B, HNF1 homeobox B, 6928

N. diseases: 279; N. variants: 72
Disease: Prostate carcinoma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs7501939
rs7501939
Entrez Id: 6928
Gene Symbol: HNF1B
HNF1B
CUI: C0600139
Disease:
Prostate carcinoma 		0.740 GeneticVariation BEFREE There was a strong significant association between rs7501939 G and the risk of prostate cancer (OR = 1.201, p = 9.31 × 10<sup>- 31</sup>). 30053805 2018
dbSNP: rs7501939
rs7501939
Entrez Id: 6928
Gene Symbol: HNF1B
HNF1B
CUI: C0600139
Disease:
Prostate carcinoma 		C 0.740 GeneticVariation GWASCAT A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences. 26034056 2015
dbSNP: rs7501939
rs7501939
Entrez Id: 6928
Gene Symbol: HNF1B
HNF1B
CUI: C0600139
Disease:
Prostate carcinoma 		0.740 GeneticVariation GWASCAT Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population. 20676098 2010
dbSNP: rs7501939
rs7501939
Entrez Id: 6928
Gene Symbol: HNF1B
HNF1B
CUI: C0600139
Disease:
Prostate carcinoma 		0.740 GeneticVariation BEFREE Three HNF1B SNPS, rs11649743, rs4430796, and rs7501939, were associated with decreased risk of prostate cancer and were also associated, with marginal statistical significance, with increased risk of diabetes. 19998368 2010
dbSNP: rs7501939
rs7501939
Entrez Id: 6928
Gene Symbol: HNF1B
HNF1B
CUI: C0600139
Disease:
Prostate carcinoma 		0.740 GeneticVariation BEFREE Similarly for rs7501939 the per-T2D-risk-allele odds ratios (95% confidence intervals) were 0.80 (0.77, 0.83) per T allele for prostate cancer (p<10(-15) for both); and 1.00 (0.97, 1.04) for all other cancers. 20526366 2010
dbSNP: rs7501939
rs7501939
Entrez Id: 6928
Gene Symbol: HNF1B
HNF1B
CUI: C0600139
Disease:
Prostate carcinoma 		0.740 GeneticVariation GWASCAT Identification of seven new prostate cancer susceptibility loci through a genome-wide association study. 19767753 2009
dbSNP: rs7501939
rs7501939
Entrez Id: 6928
Gene Symbol: HNF1B
HNF1B
CUI: C0600139
Disease:
Prostate carcinoma 		C 0.740 GeneticVariation GWASCAT Multiple newly identified loci associated with prostate cancer susceptibility. 18264097 2008
dbSNP: rs7501939
rs7501939
Entrez Id: 6928
Gene Symbol: HNF1B
HNF1B
CUI: C0600139
Disease:
Prostate carcinoma 		0.740 GeneticVariation BEFREE SNPs rs4430796 and rs7501939, which were in strong linkage disequilibrium (r(2) = 0.68), showed the strongest evidence of prostate cancer association. 18701471 2008