TCF3, transcription factor 3, 6929

N. diseases: 244; N. variants: 8
Disease: Adult Hodgkin Lymphoma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1860661
rs1860661
Entrez Id: 6929
Gene Symbol: TCF3
TCF3
CUI: C0220597
Disease:
Adult Hodgkin Lymphoma 		0.010 GeneticVariation BEFREE We identify a novel variant at 19p13.3 associated with HL (rs1860661; odds ratio (OR)=0.81, 95% confidence interval (95% CI) = 0.76-0.86, P(combined) = 3.5 × 10(-10)), located in intron 2 of TCF3 (also known as E2A), a regulator of B- and T-cell lineage commitment known to be involved in HL pathogenesis. 24920014 2014