Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1225404
rs1225404
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
CUI: C0006142
Disease:
Malignant neoplasm of breast
0.020 GeneticVariation BEFREE The C allele of rs1225404 was associated with increased breast cancer risk (OR = 1.58, P = 0.0004, PC= 0.0012), whereas the G allele of rs7003146 was associated with decreased breast cancer risk (OR = 0.71, P = 0.01, PC= 0.03). 27738320 2016
dbSNP: rs1225404
rs1225404
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
CUI: C0006142
Disease:
Malignant neoplasm of breast
0.020 GeneticVariation BEFREE After adjusting for multiple comparisons, four TCF7L2 SNPs were significantly associated with breast cancer overall: rs7903146 (OR(TT) 1.24; 95 % CI 1.03-1.49), rs3750805 (OR(AT/TT) 1.15; 95 % CI 1.03-1.28), rs7900150 (OR(AA) 1.23; 95 % 1.07-1.42), and rs1225404 (OR(CC) 0.82; 95 % 0.70-0.94). 23085767 2012