TCF7L2, transcription factor 7 like 2, 6934

N. diseases: 257; N. variants: 70
Disease: Diabetes ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs290481
rs290481
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
CUI: C0011847
Disease:
Diabetes 		0.020 GeneticVariation BEFREE T2D-related variants HHEX rs7923837, TCF7L2 rs290481 and CDKAL1 rs7756992 increased cancer risk in patients with diabetes. 24468095 2014
dbSNP: rs290481
rs290481
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
CUI: C0011847
Disease:
Diabetes 		0.020 GeneticVariation BEFREE Over an average follow-up period of 5.43 years, participants with the rs7903146 T allele or variants in the same LD block, but not those with the rs290481 G allele, were more likely to progress to diabetes (hazard ratio = 2.61, 95% confidence interval, 1.27-5.39, P = 0.009) than were non-carriers. 19806338 2010