TCF7L2, transcription factor 7 like 2, 6934

N. diseases: 257; N. variants: 70
Disease: Diabetes Mellitus, Non-Insulin-Dependent ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10885409
rs10885409
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.720 GeneticVariation BEFREE Our case-control study is the first of its kind in Emiratis which establishes TCF7L2 rs10885409 C allele as a T2DM risk factor in Emiratis and this association is modulated by obesity status. 26273662 2015
dbSNP: rs10885409
rs10885409
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.720 GeneticVariation GWASDB Identification of susceptibility genes for complex diseases using pooling-based genome-wide association scans. 19184112 2009
dbSNP: rs10885409
rs10885409
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.720 GeneticVariation BEFREE We report replication of association of four of the six SNPs with T2DM in this Khatri Sikh sample [rs7903146, (p = 0.010); rs11196205, (p = 0.011); rs10885409, (p = 0.002) and rs4918789, (p = 0.029)], under a dominant model conferring odds ratios (ORs) of 1.39, 1.44, 1.57 and 1.36, respectively. 18397358 2008
dbSNP: rs10885409
rs10885409
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.720 GeneticVariation GWASDB A genome-wide association study identifies novel risk loci for type 2 diabetes. 17293876 2007