TGFA, transforming growth factor alpha, 7039

N. diseases: 376; N. variants: 10
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs432203
rs432203
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
CUI: C0023980
Disease:
Longevity
0.800 GeneticVariation GWASCAT Joint influence of small-effect genetic variants on human longevity. 20834067 2010
dbSNP: rs432203
rs432203
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
CUI: C0023980
Disease:
Longevity
0.800 GeneticVariation GWASDB Joint influence of small-effect genetic variants on human longevity. 20834067 2010
dbSNP: rs3771501
rs3771501
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
CUI: C0029408
Disease:
Degenerative polyarthritis
G 0.700 GeneticVariation GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745 2019
dbSNP: rs3771501
rs3771501
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
CUI: C0029408
Disease:
Degenerative polyarthritis
A 0.700 GeneticVariation GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745 2019
dbSNP: rs3821262
rs3821262
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
CUI: C0409959
Disease:
Osteoarthritis, Knee
A 0.700 GeneticVariation GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745 2019
dbSNP: rs3821262
rs3821262
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
CUI: C0029410
Disease:
Osteoarthritis of hip
A 0.700 GeneticVariation GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745 2019
dbSNP: rs7571789
rs7571789
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
CUI: C0029410
Disease:
Osteoarthritis of hip
T 0.700 GeneticVariation GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745 2019
dbSNP: rs3771501
rs3771501
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
CUI: C0029408
Disease:
Degenerative polyarthritis
A 0.700 GeneticVariation GWASCAT Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis. 29559693 2018
dbSNP: rs3771501
rs3771501
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
CUI: C0029410
Disease:
Osteoarthritis of hip
0.700 GeneticVariation GWASCAT Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritis. 30374069 2018
dbSNP: rs79070520
rs79070520
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
CUI: C3893645
Disease:
response to ACE inhibitor
0.700 GeneticVariation GWASCAT Genetic variants associated with angiotensin-converting enzyme inhibitor-induced cough: a genome-wide association study in a Swedish population. 28084903 2017
dbSNP: rs2862851
rs2862851
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
CUI: C0029408
Disease:
Degenerative polyarthritis
0.010 GeneticVariation BEFREE Our findings suggest that the rs2862851 allele of the TGFA gene may significantly contribute to the susceptibility to knee OA in the Han Chinese population. 28777012 2017
dbSNP: rs11466285
rs11466285
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
CUI: C4321245
Disease:
Cleft lip or lips
0.010 GeneticVariation BEFREE To investigate the association between the TGFA:c.3851T > C (rs11466285) and TGFA:c.3822G > A (rs3771523) single-nucleotide polymorphisms (SNPs) and nonsyndromic cleft lip and/or cleft palate (CL/P) with microarray in north China. 23742131 2014
dbSNP: rs11466285
rs11466285
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
CUI: C0008925
Disease:
Cleft Palate
0.010 GeneticVariation BEFREE To investigate the association between the TGFA:c.3851T > C (rs11466285) and TGFA:c.3822G > A (rs3771523) single-nucleotide polymorphisms (SNPs) and nonsyndromic cleft lip and/or cleft palate (CL/P) with microarray in north China. 23742131 2014
dbSNP: rs11466285
rs11466285
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
CUI: C2981150
Disease:
Uranostaphyloschisis
0.010 GeneticVariation BEFREE To investigate the association between the TGFA:c.3851T > C (rs11466285) and TGFA:c.3822G > A (rs3771523) single-nucleotide polymorphisms (SNPs) and nonsyndromic cleft lip and/or cleft palate (CL/P) with microarray in north China. 23742131 2014
dbSNP: rs11466285
rs11466285
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
CUI: C0008924
Disease:
Cleft upper lip
0.010 GeneticVariation BEFREE To investigate the association between the TGFA:c.3851T > C (rs11466285) and TGFA:c.3822G > A (rs3771523) single-nucleotide polymorphisms (SNPs) and nonsyndromic cleft lip and/or cleft palate (CL/P) with microarray in north China. 23742131 2014
dbSNP: rs11466285
rs11466285
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
CUI: C1837218
Disease:
Cleft palate, isolated
0.010 GeneticVariation BEFREE To investigate the association between the TGFA:c.3851T > C (rs11466285) and TGFA:c.3822G > A (rs3771523) single-nucleotide polymorphisms (SNPs) and nonsyndromic cleft lip and/or cleft palate (CL/P) with microarray in north China. 23742131 2014
dbSNP: rs3732253
rs3732253
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
CUI: C3150911
Disease:
GASTRIC CANCER, INTESTINAL
0.010 GeneticVariation BEFREE CT/TT genotype for rs3732253 in the 3' UTR was associated with increased risk of intestinal gastric cancer (adjusted OR = 1.464, 95%CI: 1.036-2.069), compared to their wild homozygous genotypes. 24237184 2014
dbSNP: rs3771523
rs3771523
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
CUI: C1837218
Disease:
Cleft palate, isolated
0.010 GeneticVariation BEFREE To investigate the association between the TGFA:c.3851T > C (rs11466285) and TGFA:c.3822G > A (rs3771523) single-nucleotide polymorphisms (SNPs) and nonsyndromic cleft lip and/or cleft palate (CL/P) with microarray in north China. 23742131 2014
dbSNP: rs3771523
rs3771523
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
CUI: C4321245
Disease:
Cleft lip or lips
0.010 GeneticVariation BEFREE To investigate the association between the TGFA:c.3851T > C (rs11466285) and TGFA:c.3822G > A (rs3771523) single-nucleotide polymorphisms (SNPs) and nonsyndromic cleft lip and/or cleft palate (CL/P) with microarray in north China. 23742131 2014
dbSNP: rs3771523
rs3771523
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
CUI: C0008924
Disease:
Cleft upper lip
0.010 GeneticVariation BEFREE To investigate the association between the TGFA:c.3851T > C (rs11466285) and TGFA:c.3822G > A (rs3771523) single-nucleotide polymorphisms (SNPs) and nonsyndromic cleft lip and/or cleft palate (CL/P) with microarray in north China. 23742131 2014
dbSNP: rs3771523
rs3771523
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
CUI: C0008925
Disease:
Cleft Palate
0.010 GeneticVariation BEFREE To investigate the association between the TGFA:c.3851T > C (rs11466285) and TGFA:c.3822G > A (rs3771523) single-nucleotide polymorphisms (SNPs) and nonsyndromic cleft lip and/or cleft palate (CL/P) with microarray in north China. 23742131 2014
dbSNP: rs3771523
rs3771523
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
CUI: C2981150
Disease:
Uranostaphyloschisis
0.010 GeneticVariation BEFREE To investigate the association between the TGFA:c.3851T > C (rs11466285) and TGFA:c.3822G > A (rs3771523) single-nucleotide polymorphisms (SNPs) and nonsyndromic cleft lip and/or cleft palate (CL/P) with microarray in north China. 23742131 2014
dbSNP: rs2166975
rs2166975
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
CUI: C0007789
Disease:
Cerebral Palsy
0.010 GeneticVariation BEFREE Associations were found between the TGFA gene marker rs2166975 and nonsyndromic cleft palate only (CPO) phenotype (p = 0.045, df 1) as well as between the D2S292 marker and the cleft lip with or without cleft palate (CL/CP) phenotype in allele-wise TDT (P = 0.005, df 9) and genotype-wise TDT (P = 0.021, df 24). 17272867 2007
dbSNP: rs2166975
rs2166975
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
CUI: C2981150
Disease:
Uranostaphyloschisis
0.010 GeneticVariation BEFREE Associations were found between the TGFA gene marker rs2166975 and nonsyndromic cleft palate only (CPO) phenotype (p = 0.045, df 1) as well as between the D2S292 marker and the cleft lip with or without cleft palate (CL/CP) phenotype in allele-wise TDT (P = 0.005, df 9) and genotype-wise TDT (P = 0.021, df 24). 17272867 2007
dbSNP: rs2166975
rs2166975
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
CUI: C0008925
Disease:
Cleft Palate
0.010 GeneticVariation BEFREE Associations were found between the TGFA gene marker rs2166975 and nonsyndromic cleft palate only (CPO) phenotype (p = 0.045, df 1) as well as between the D2S292 marker and the cleft lip with or without cleft palate (CL/CP) phenotype in allele-wise TDT (P = 0.005, df 9) and genotype-wise TDT (P = 0.021, df 24). 17272867 2007