TIMP2, TIMP metallopeptidase inhibitor 2, 7077

N. diseases: 404; N. variants: 20
Disease: Breast Carcinoma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4789936
rs4789936
Entrez Id: 7077;100653515
Gene Symbol: TIMP2;CEP295NL
TIMP2;CEP295NL
CUI: C0678222
Disease:
Breast Carcinoma 		0.010 GeneticVariation BEFREE Bioinformatics analysis found that rs4789936 was likely to affect transcription factor binding, motifs, DNase footprint, and DNase peaks; and TIMP-2 was under-expressed in breast cancer, the risk allele of rs4789936 was associated with increased expression of TIMP-2 in peripheral blood samples. 31088428 2019