TNF, tumor necrosis factor, 7124

N. diseases: 2724; N. variants: 31
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs745738344
rs745738344
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0027051
Disease:
Myocardial Infarction
0.020 GeneticVariation BEFREE We investigated the possibility that single nucleotide polymorphisms of the genes encoding TNF-alpha (-863C/A, -308G/A), LT-alpha (252G/A), and IL-10 (-1082G/A, -819C/T, and -592C/A) are associated with the incidence of restenosis, death, or myocardial infarction (MI) after coronary stenting. 14572794 2003
dbSNP: rs745738344
rs745738344
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0027051
Disease:
Myocardial Infarction
0.020 GeneticVariation BEFREE The emerging data are quite conflicting and do not provide definitive evidence for a role of these gene variants in the pathogenesis of IHD; a possible exception is the G252A and polymorphism in the TNF-beta gene (also known as lymphotoxin-alpha) which, in a comprehensive genome-scan linkage analysis of unrelated Japanese, but not in a smaller German population, was linked to myocardial infarction. 15760675 2005
dbSNP: rs1800629
rs1800629
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0027051
Disease:
Myocardial Infarction
0.010 GeneticVariation BEFREE Association between TNF-α rs1800629 polymorphism and the risk of myocardial infarction: A meta-analysis. 27706628 2016