TNF, tumor necrosis factor, 7124

N. diseases: 2724; N. variants: 31
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1799724
rs1799724
Entrez Id: 4049;7124
Gene Symbol: LTA;TNF
LTA;TNF
CUI: C0028754
Disease:
Obesity
0.010 GeneticVariation BEFREE Our aim was to study the role of TNF-α in the pathogenesis of IR and Ob in PCOS, as well as a C850T (rs1799724) polymorphism in the promoter region of the TNF-α gene, in a group of 204 PCOS patients and 204 age-matched healthy controls. 25083576 2014
dbSNP: rs361525
rs361525
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0028754
Disease:
Obesity
0.010 GeneticVariation BEFREE ME attenuated the influence of APOB rs512535 and TNFA rs361525 on obesity risk in FMP.WC was significantly associated to GRS. 28294290 2017
dbSNP: rs763000109
rs763000109
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0028754
Disease:
Obesity
0.010 GeneticVariation BEFREE The MnSOD Ala16Val single nucleotide polymorphism (SNP) has shown to be associated to inflammatory pathways and many metabolic disorders, such as obesity and dyslipidemia. 31212050 2019