TNF, tumor necrosis factor, 7124

N. diseases: 2724; N. variants: 31
Disease: Obesity ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs763000109
rs763000109
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0028754
Disease:
Obesity 		0.010 GeneticVariation BEFREE The MnSOD Ala16Val single nucleotide polymorphism (SNP) has shown to be associated to inflammatory pathways and many metabolic disorders, such as obesity and dyslipidemia. 31212050 2019
dbSNP: rs361525
rs361525
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0028754
Disease:
Obesity 		0.010 GeneticVariation BEFREE ME attenuated the influence of APOB rs512535 and TNFA rs361525 on obesity risk in FMP.WC was significantly associated to GRS. 28294290 2017
dbSNP: rs1799724
rs1799724
Entrez Id: 4049;7124
Gene Symbol: LTA;TNF
LTA;TNF
CUI: C0028754
Disease:
Obesity 		0.010 GeneticVariation BEFREE Our aim was to study the role of TNF-α in the pathogenesis of IR and Ob in PCOS, as well as a C850T (rs1799724) polymorphism in the promoter region of the TNF-α gene, in a group of 204 PCOS patients and 204 age-matched healthy controls. 25083576 2014