TNF, tumor necrosis factor, 7124

N. diseases: 2724; N. variants: 31
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs361525
rs361525
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0033860
Disease:
Psoriasis
0.030 GeneticVariation BEFREE After correction for multiple testing with a false discovery rate of 5%, two SNPs remained significant: TNF (rs361525) was associated with PsO, PsC10, and PsA; and IL12B (rs6887695) was associated with PsO. 29389950 2018
dbSNP: rs1800629
rs1800629
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0033860
Disease:
Psoriasis
0.020 GeneticVariation BEFREE An association was found between rs1800629 (TNF-α) and Type I psoriasis, and rs833061 (VEGF) and Type II psoriasis. 31148856 2020
dbSNP: rs361525
rs361525
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0033860
Disease:
Psoriasis
0.030 GeneticVariation BEFREE Association of the tumour necrosis factor-α polymorphisms rs361525 and rs1800629 with susceptibility to psoriasis: a meta-analysis. 24252077 2013
dbSNP: rs1800629
rs1800629
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0033860
Disease:
Psoriasis
0.020 GeneticVariation BEFREE Association of the tumour necrosis factor-α polymorphisms rs361525 and rs1800629 with susceptibility to psoriasis: a meta-analysis. 24252077 2013
dbSNP: rs982610810
rs982610810
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0033860
Disease:
Psoriasis
0.010 GeneticVariation BEFREE By contrast, healthy individuals homozygous for the common variant D10N, located in the ACT1 tumor necrosis factor receptor-associated factor-interacting domain and previously associated with psoriasis, had impaired, but not abolished, responses to IL-17 cytokines. 24120361 2013
dbSNP: rs1799964
rs1799964
Entrez Id: 4049;7124;100287329
Gene Symbol: LTA;TNF;LOC100287329
LTA;TNF;LOC100287329
CUI: C0033860
Disease:
Psoriasis
0.010 GeneticVariation BEFREE Haplotype analysis suggests that the coexistence of the polymorphisms rs1799964 (TNF-α), rs2010963 (VEGF), rs833061 (VEGF), and rs6311 (5HT2A) may be a protective factor for psoriasis. 31148856 2020
dbSNP: rs361525
rs361525
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0033860
Disease:
Psoriasis
0.030 GeneticVariation BEFREE Tumor necrosis factor alpha (TNFα) gene -238G/A polymorphism (rs361525) is associated with psoriasis in several populations worldwide. 28093730 2017